- Search results for Cay10008612-%25
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7 products were found matching "Cay10008612-%25"!
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Item number: Cay10008613-25
Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARalpha results in expression of a variety of genes, particularly those involved in fatty acid beta-oxidation, binding, and transport. GW 7647 is a...
Keywords: | 2-methyl-2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-propanoic acid |
Application: | PPARalpha agonist |
CAS | 265129-71-3 |
MW: | 502.8 D |
From 50.00€
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Item number: Cay10008617-25
Arachidonic acid leelamide is the arachidonic amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with...
Keywords: | 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrene-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
MW: | 571.9 D |
From 72.00€
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Item number: Cay10008610-25
Soluble epoxide hydrolase (sEH) catalyzes the conversion of epoxyeicosatrienoic acids (EpETrEs) to the corresponding DiHETrEs thereby diminishing their vasodilator activity. Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation. Epoxy fluor 7 is a sensitive...
Keywords: | cyano(6-methoxy-2-napthalenyl)methyl[(2,3)-3-phenyloxiranyl]methyl ester, carbonic acid |
Application: | Fluorescent sEH substrate |
CAS | 863223-43-2 |
MW: | 389.4 D |
From 54.00€
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Item number: Cay10008671-25
Sildenafil is a potent inhibitor of phosphodiesterase 5 (PDE5) with IC50 values of 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively. It is selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 µM, respectively). Sildenafil reverses glucose-induced decreases...
Keywords: | 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one |
Application: | PDE5 inhibitor |
CAS | 139755-83-2 |
MW: | 474.6 D |
From 64.00€
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Item number: Cay10008602-25
Arachidonoyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism of AEA by...
Keywords: | 20-hydroxy AEA, 20-hydroxy Arachidonoyl Ethanolamide, 20-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | CYP450 metabolism studies |
CAS | 942069-11-6 |
MW: | 363.5 D |
From 310.00€
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Item number: Cay10008642-25
AEA acts as an endogenous mimic of Delta9-THC, the psychotropic component of marijuana. oxy-AEA is the O-alkyl-N-acyl oxyhomologue of AEA. oxy-AEA is selective for the peripheral cannabinoid (CB2) receptor with Ki values of 0.47 and 0.081 µM for hCB1 and hCB2, respectively. In comparison, AEA has a greater affinity...
Keywords: | oxy-AEA, oxy-Anandamide, N-(2-hydroxyethoxy)-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 883296-70-6 |
MW: | 363.5 D |
From 84.00€
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Item number: Cay10008652-25
(±)-alpha-CMBHC is a metabolite of (±)-alpha-tocopherol (Cay-25985).Formal Name: 3,4-dihydro-6-hydroxy-alpha,2,5,7,8-pentamethyl-2H-1-benzopyran-2-pentanoic acid. CAS Number: 7083-09-2. Molecular Formula: C19H28O4. Formula Weight: 320.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid....
Keywords: | 3,4-dihydro-6-hydroxy-alpha,2,5,7,8-pentamethyl-2H-1-benzopyran-2-pentanoic acid |
Application: | Bioactive lipid assays |
CAS | 7083-09-2 |
MW: | 320.4 D |
From 53.00€
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