4 products were found matching "Cay10008443-%25"!
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CAY10443
Item number: Cay10004177-25
Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is...
| Keywords: | (S)-Indan-1-yl 3,4-dichlorobenzylcarbamate, [(3,4-dichlorophenyl)methyl]-carbamic acid, (1S)-2,3-dihydro-1H-inden-1-yl ester |
| Application: | Caspase-3 activator |
| CAS | 582314-48-5 |
| MW: | 336.2 D |
From 66.00€
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Prostaglandin F2alpha-d9
Item number: Cay10008643-25
Prostaglandin F2alpha-d9 (PGF2alpha-d9) is intended for use as an internal standard for the quantification of PGF2alpha (Cay-16010) by GC- or LC-ms. PGF2alpha is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also...
| Keywords: | Dinoprost-d9, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid |
| Application: | Standard |
| MW: | 363.5 D |
From 65.00€
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16(S)-HETE
Item number: Cay10004384-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase...
| Keywords: | 16S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 183509-23-1 |
| MW: | 320.5 D |
From 196.00€
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SB939
Item number: Cay10443-25
SB939 is a pan-inhibitor of histone deacetylases (HDACs, Kis = 16-247 nM for HDAC1-11). It inhibits proliferation of A2780, COLO 205, HCT116, and PC3 cancer cells (IC50s = 0.48, 0.56, 0.48, and 0.34 µM, respectively). SB939 (50 and 100 mg/kg) reduces tumor growth and increases survival in an HCT116 mouse xenograft...
| Keywords: | Pracinostat, 3-[2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2E-propenamide |
| Application: | HDAC inhibitor |
| CAS | 929016-96-6 |
| MW: | 358.5 D |
From 60.00€
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