3 products were found matching "Cay10008427-%25"!
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D-myo-Inositol-2,5,6-triphosphate (sodium salt)
Item number: Cay10008424-500
Ins(2,5,6)P3 (sodium salt) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of...
| Keywords: | 2,5,6-IP3 (sodium salt), Ins(2,5,6)P3 (sodium salt), D-myo-inositol-2,5,6-tris(dihydrogen phosphate), trisodium salt |
| Application: | Bioactive lipid assays |
| MW: | 486 D |
From 84.00€
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Sulindac sulfide
Item number: Cay10004387-25
Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
| Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid |
| Application: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
| CAS | 49627-27-2 |
| MW: | 340.4 D |
From 43.00€
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Lubiprostone
Item number: Cay10010487-25
Lubiprostone is an activator of chloride channel protein 2 (ClC-2) and a bicyclic derivative of prostaglandin E1 (PGE1, Cay-13010). It induces chloride currents in HEK293 cells expressing recombinant human ClC-2 (EC50 = ~17 nM), but not CFTR, chloride channels. Lubiprostone (1 µM) induces short-circuit currents, a...
| Keywords: | RU-0211, SPI-0211, 16,16-difluoro-11alpha-hydroxy-9,15-dioxo-prostan-1-oic acid |
| Application: | ClC-2 activator |
| CAS | 136790-76-6 |
| MW: | 390.5 D |
From 84.00€
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