- Search results for Cay10008197-%25
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5 products were found matching "Cay10008197-%25"!
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Item number: Cay10008187-25
Dimethylcurcumin is a selective enhancer of androgen receptor (AR) degradation. By disrupting the interaction between AR and its coregulators, dimethylcurcumin directs the degradation of AR and reduces signaling through this receptor both in cultured cells and in animals. In this way, dimethylcurcumin suppresses the...
Keywords: | (1E,4Z)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6E-heptatrien-3-one |
Application: | Androgen receptor (AR) degradation enhancer |
CAS | 52328-98-0 |
MW: | 396.4 D |
From 60.00€
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Item number: Cay10009817-25
Pleckstrin homology (PH) domains all contain a seven-standard beta-sandwich that allows binding to various species of phosphatidyl inositol (PtdIns) phosphates. Most PH domains bind to PtdIns phosphates with weak affinity and low specificity. However, a small subclass binds specifically and with high-affinity for...
Keywords: | Grp1, Grp1, ARNO3, Cytohesin-3, Cytohesin-3, Protein ARNO3, Protein ARNO3, ARF nucleotide-binding site opener 3, ARF... |
Application: | WB |
MW: | 41,7 kD |
From 189.00€
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Item number: Cay10008597-25
Arachidonoyl ethanolamide (AEA, anandamide) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism...
Keywords: | (±)8,9-EET Ethanolamide, N-(2-hydroxyethyl)-(±)8(9)-epoxy-5Z,11Z,14Z-eicosatrienoic amide |
Application: | Bioactive lipid assays |
MW: | 363.5 D |
From 119.00€
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Item number: Cay10009197-25
Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
Keywords: | Alvocidib, HL 275, HMR 1275, L-868,275,... |
CAS | 131740-09-5 |
MW: | 438.3 D |
From 66.00€
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Item number: Cay10006197-25
Leukotriene A4-d5 (LTA4-d5) methyl ester contains four deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of LTA4 methyl ester by GC- or LC-mass spectrometry. LTA4 is synthesized in mast cells, eosinophils, and neutrophils from arachidonic...
Keywords: | LTA4-d5 methyl ester, 5S-trans-5,6-oxido-7E,9E,11Z,14Z-eicosatetraenoic-19,19,20,20, and 20-d5 acid, methyl ester |
Application: | Standard |
MW: | 337.5 D |
From 390.00€
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