- Search results for Cay10008127-%25
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7 products were found matching "Cay10008127-%25"!
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Item number: Cay10008187-25
Dimethylcurcumin is a selective enhancer of androgen receptor (AR) degradation. By disrupting the interaction between AR and its coregulators, dimethylcurcumin directs the degradation of AR and reduces signaling through this receptor both in cultured cells and in animals. In this way, dimethylcurcumin suppresses the...
Keywords: | (1E,4Z)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6E-heptatrien-3-one |
Application: | Androgen receptor (AR) degradation enhancer |
CAS | 52328-98-0 |
MW: | 396.4 D |
From 60.00€
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Item number: Cay10008128-25
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase...
Keywords: | 10(S),17(S)-DiHDoHE, PDX, Protectin DX, 10(S),17(S)-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid |
Application: | Bioactive lipid assays |
CAS | 871826-47-0 |
MW: | 360.5 D |
From 244.00€
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Item number: Cay10008120-25
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the...
Keywords: | Suc-LY-AMC, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide |
Application: | Fluorescent calpain I & II & papain & 20S proteasome substrate |
CAS | 94367-20-1 |
MW: | 551.6 D |
From 50.00€
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Item number: Cay10007187-25
Microcystin-LA is a cyanotoxin and an inhibitor of protein phosphatase 1C (PP1C) and PP2A (IC50 = 0.3 nM for both). In vivo, microcystin-LA (7 mg/kg) induces moribundity and increases liver-to-body weight ratios and serum levels of alanine transaminase (ALT), aspartate aminotransferase (AST), and glutamate...
Keywords: | Cyanoginosin-LA, Toxin BE4 (M. aeruginosa),... |
Application: | PP1C and PP2A inhibitor |
CAS | 96180-79-9 |
MW: | 910.1 D |
From 254.00€
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Item number: Cay10008517-25
Cytochrome P450 enzymes function to metabolize both endogenous and exogenous compounds. Both the 3A and 2C isoforms are present in human liver of which CYP2C9 seems most highly expressed. Tienilic acid is a specific suicide substrate for CYP2C9 and CYP2C10 whereby its oxidation inactivates the enzyme. The time...
Keywords: | [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]-acetic acid |
Application: | CYP2C9 /CYP2C10 substrate |
CAS | 40180-04-9 |
MW: | 331.2 D |
From 97.00€
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Item number: Cay10008671-25
Sildenafil is a potent inhibitor of phosphodiesterase 5 (PDE5) with IC50 values of 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively. It is selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 µM, respectively). Sildenafil reverses glucose-induced decreases...
Keywords: | 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one |
Application: | PDE5 inhibitor |
CAS | 139755-83-2 |
MW: | 474.6 D |
From 64.00€
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Item number: Cay10008617-25
Arachidonic acid leelamide is the arachidonic amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with...
Keywords: | 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrene-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
MW: | 571.9 D |
From 72.00€
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