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Cay10007974-10
FK-​506 analog Erklärungen der Abkürzungen ansehen.
Synthetic ligand of FKBP (SLF) is a cell-permeable analog of FK-506 that binds tightly to FKBP but lacks the ability to inhibit calcineurin. By itself, SLF does not exhibit a significant cellular response. However, homodimers of SLF or heterodimers with another protein ligand, provide a method to promote the dimerization of ligand-specific fusion proteins to induce signaling events within a cellular environment. For example, SLF monomers connected with a 10-atom linker activates Fas signaling via Fas-FKBP fusion proteins with an EC50 of 6 nM.

MW: 524 D
Formula: C30H40N2O6
Purity: >98%
Cayman
Icon Datasheet
10 mg

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164 €

Cay10007974-100
FK-​506 analog Erklärungen der Abkürzungen ansehen.
Synthetic ligand of FKBP (SLF) is a cell-permeable analog of FK-506 that binds tightly to FKBP but lacks the ability to inhibit calcineurin. By itself, SLF does not exhibit a significant cellular response. However, homodimers of SLF or heterodimers with another protein ligand, provide a method to promote the dimerization of ligand-specific fusion proteins to induce signaling events within a cellular environment. For example, SLF monomers connected with a 10-atom linker activates Fas signaling via Fas-FKBP fusion proteins with an EC50 of 6 nM.

MW: 524 D
Formula: C30H40N2O6
Purity: >98%
Cayman
Icon Datasheet
100 mg

Buy Bulk

1202 €

Cay10007974-5
FK-​506 analog Erklärungen der Abkürzungen ansehen.
Synthetic ligand of FKBP (SLF) is a cell-permeable analog of FK-506 that binds tightly to FKBP but lacks the ability to inhibit calcineurin. By itself, SLF does not exhibit a significant cellular response. However, homodimers of SLF or heterodimers with another protein ligand, provide a method to promote the dimerization of ligand-specific fusion proteins to induce signaling events within a cellular environment. For example, SLF monomers connected with a 10-atom linker activates Fas signaling via Fas-FKBP fusion proteins with an EC50 of 6 nM.

MW: 524 D
Formula: C30H40N2O6
Purity: >98%
Cayman
Icon Datasheet
5 mg

Buy Bulk

86 €

Cay10007974-50
FK-​506 analog Erklärungen der Abkürzungen ansehen.
Synthetic ligand of FKBP (SLF) is a cell-permeable analog of FK-506 that binds tightly to FKBP but lacks the ability to inhibit calcineurin. By itself, SLF does not exhibit a significant cellular response. However, homodimers of SLF or heterodimers with another protein ligand, provide a method to promote the dimerization of ligand-specific fusion proteins to induce signaling events within a cellular environment. For example, SLF monomers connected with a 10-atom linker activates Fas signaling via Fas-FKBP fusion proteins with an EC50 of 6 nM.

MW: 524 D
Formula: C30H40N2O6
Purity: >98%
Cayman
Icon Datasheet
50 mg

Buy Bulk

687 €


 

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