- Search results for Cay10007950
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15 products were found matching "Cay10007950"!
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Item number: Cay10007779-500
The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, D-myo-Inositol-2,4,5-triphosphate...
Keywords: | 2,4,5-IP3 (sodium salt), Ins(2,4,5)P3 (sodium salt), D-myo-inositol-2,4,5-tris(hydrogen phosphate), trisodium salt |
Application: | Ins(1,4,5)-P3 analog |
MW: | 486 D |
From 84.00€
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Item number: Cay10007983-50
Corey lactone benzoate is a precursor that has been used in the synthesis of prostaglandins (PGs), as well as the agonist of the PGE2 receptor subtype EP4 rivenprost (Cay-13618).Formal Name: (3aR,4S,5R,6aS)-5-(benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. CAS Number: 39746-00-4. Synonyms:...
Keywords: | (-)-Corey Lactone Benzoate, (-)-Corey Lactone Benzoate Alcohol,... |
Application: | Prostaglandin synthetis precursor |
CAS | 39746-00-4 |
MW: | 276.3 D |
From 35.00€
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Item number: Cay10007974-50
FK-506 is a potent immunosuppressant that forms a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation. Synthetic ligand of FKBP (SLF) is a...
Keywords: | Synthetic Ligand of FKBP, 1-(3,3-dimethyl-1,2-dioxopentyl)-(2S)-2-piperidinecarboxylic acid,... |
Application: | FK-506 analog |
CAS | 195513-96-3 |
MW: | 524.7 D |
From 123.00€
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Item number: Cay10007965-50
FK-506 is a potent immunosuppressant in the same molecular class as cyclosporin A (Cay-12088) and rapamycin (Cay-13346). Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex then inhibits the activity of the...
Keywords: | Tacrolimus,... |
Application: | Immunosuppressant |
CAS | 104987-11-3 |
MW: | 804 D |
From 48.00€
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Item number: Cay10007907-50
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces...
Keywords: | (-)-Sphingosine, D-erythro-Sphingosine C-18, 2S-amino-4E-octadecene-1,3R-diol |
Application: | Bioactive lipid assays |
CAS | 123-78-4 |
MW: | 299.5 D |
From 60.00€
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Item number: Cay10007945-50
Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins, as well as in some cancers. Sphinganine can block protein kinase C...
Keywords: | D-erythro-Dihydrosphingosine, D-erythro-Sphinganine, Dihydro-D-erythro Sphingosine, Dihydrosphingosine, Sphinganine,... |
Application: | Sphingolipid studies |
CAS | 764-22-7 |
MW: | 301.5 D |
From 48.00€
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Item number: Cay10007975-50
(±)11(12)-DiHET-d11 is intended for use as an internal standard for the quantification of 11(12)-DiHET by GC- or LC-MS. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formed via enzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.Formal Name:...
Keywords: | (±)11(12)-DHET-d11, (±)11,12-DiHETrE-d11,... |
Application: | Standard |
MW: | 349.6 D |
From 244.00€
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Item number: Cay10007980-50
Local catabolism of the amino acid tryptophan by indoleamine 2,3-dioxygenase (IDO) is considered an important mechanism of regulating T-cell immunity. Inhibition of the production of T helper-1 (TH1) cytokines offers a new strategy for treating TH1 mediated autoimmune diseases such as multiple sclerosis. 3,4-DAA is...
Keywords: | 2-[3-(3,4-dimethoxy-phenyl)-acryloylamino]-3-hydroxy-benzoic acid |
Application: | Metabolic studies |
CAS | 2117759-07-4 |
MW: | 343.3 D |
From 24.00€
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Item number: Cay10007923-50
Epoxyeicosatrienoic acid (EpETrE, EET) metabolites of arachidonic acid such as 11(12)-EET and 14(15)-EET have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids...
Keywords: | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid |
Application: | sEH inhibitor |
CAS | 479413-68-8 |
MW: | 340.5 D |
From 64.00€
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COVID-19 Research
Item number: Cay10007963-50
E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities. It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the...
Keywords: | (2S,3S)-3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic... |
Application: | Cysteine protease inhibitor |
CAS | 66701-25-5 |
MW: | 357.4 D |
From 73.00€
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Item number: Cay10007912-50
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This omega-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing...
Keywords: | 20-carboxy AA, 20-COOH-AA, 5Z,8Z,11Z,14Z-eicosatetraenedioic acid |
Application: | Bioactive lipid assays |
CAS | 79551-84-1 |
MW: | 334.5 D |
From 300.00€
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Item number: Cay10007927-50
Epoxyeicosatrienoic acid (EpETrE) metabolites of arachidonic acid such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding dihydroxy eicosatrienoic...
Keywords: | 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid |
Application: | sEH inhibitor |
CAS | 479413-70-2 |
MW: | 392.6 D |
From 42.00€
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