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Sphingosine (d18:1)
Item number: Cay10007907-25
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces...
| Keywords: | (-)-Sphingosine, D-erythro-Sphingosine C-18, 2S-amino-4E-octadecene-1,3R-diol |
| Application: | Bioactive lipid assays |
| CAS | 123-78-4 |
| MW: | 299.5 D |
From 60.00€
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Lipid-based Drug Delivery Tools
D-erythro Lysosphingomyelin (d18:1)
Item number: Cay10007947-25
D-erythro Lysosphingomyelin is a bioactive sphingolipid. It is an agonist of sphingosine-1-phosphate receptor 1 (S1P1), S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors). D-erythro Lysosphingomyelin is also an agonist of the orphan receptor ovarian cancer G protein-coupled...
| Keywords: | D-erythro Lyso SM(18:1), D-erythro Sphingosine-1-Phosphocholine (d18:1), D-erythro-Sphingophosphorylcholine,... |
| Application: | Bioactive Lipid Assays |
| CAS | 1670-26-4 |
| MW: | 464.6 D |
From 121.00€
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CUDA
Item number: Cay10007923-25
Epoxyeicosatrienoic acid (EpETrE, EET) metabolites of arachidonic acid such as 11(12)-EET and 14(15)-EET have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids...
| Keywords: | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid |
| Application: | sEH inhibitor |
| CAS | 479413-68-8 |
| MW: | 340.5 D |
From 64.00€
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(±)11(12)-DiHET-d11
Item number: Cay10007975-25
(±)11(12)-DiHET-d11 is intended for use as an internal standard for the quantification of 11(12)-DiHET by GC- or LC-MS. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formed via enzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.Formal Name:...
| Keywords: | (±)11(12)-DHET-d11, (±)11,12-DiHETrE-d11,... |
| Application: | Standard |
| MW: | 349.6 D |
From 244.00€
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13,14-dihydro-15-keto Prostaglandin D2-d4
Item number: Cay10007978-25
13,14-dihydro-15-keto Prostaglandin D2-d4 (13,14-dihydro-15-keto PGD2-d4) is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2 (Cay-12610) by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGD2 is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH...
| Keywords: | 13,14-dihydro-15-keto PGD2-d4, 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| MW: | 356.5 D |
From 189.00€
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Resolvin D2
Item number: Cay10007279-25
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2, RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid |
| Application: | Lipid mediator |
| CAS | 810668-37-2 |
| MW: | 376.5 D |
From 205.00€
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