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Cylindrospermopsin
Cylindrospermopsin

Item number: Cay10007867-25

Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes...
Keywords: 6-[(R)-hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]met...
Application: Cyanobacterial toxin, uridine monophosphate synthase inhibitor
CAS 143545-90-8
MW: 415.4 D
From 212.00€ *
Review
Microcystin-LA
Microcystin-LA

Item number: Cay10007187-25

Microcystin-LA is a cyanotoxin and an inhibitor of protein phosphatase 1C (PP1C) and PP2A (IC50 = 0.3 nM for both). In vivo, microcystin-LA (7 mg/kg) induces moribundity and increases liver-to-body weight ratios and serum levels of alanine transaminase (ALT), aspartate aminotransferase (AST), and glutamate...
Keywords: Cyanoginosin-LA, Toxin BE4 (M. aeruginosa),...
Application: PP1C and PP2A inhibitor
CAS 96180-79-9
MW: 910.1 D
From 254.00€ *
Review
PtdIns-(3,4,5)-P3 Binding Protein
PtdIns-(3,4,5)-P3 Binding Protein

Item number: Cay10009817-25

Pleckstrin homology (PH) domains all contain a seven-standard beta-sandwich that allows binding to various species of phosphatidyl inositol (PtdIns) phosphates. Most PH domains bind to PtdIns phosphates with weak affinity and low specificity. However, a small subclass binds specifically and with high-affinity for...
Keywords: Grp1, Grp1, ARNO3, Cytohesin-3, Cytohesin-3, Protein ARNO3, Protein ARNO3, ARF nucleotide-binding site opener 3, ARF...
Application: WB
MW: 41,7 kD
From 189.00€ *
Review