- Search results for Cay10007784
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4 products were found matching "Cay10007784"!
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Item number: Cay10007784-100
The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second...
Keywords: | 1,3,4,5,6-IP5 (sodium salt), Ins(1,3,4,5,6)P5 (sodium salt), D-myo-inositol-1,3,4,5,6-penta(hydrogen phosphate),... |
Application: | Akt inhibitor, PKB inhibitor |
MW: | 690 D |
From 84.00€
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Item number: Cay34020-5
CAY10784 is a STAT3 inhibitor (IC50 = 0.74 µM in a reporter assay) and a derivative of WP1066 (Cay-14736). It inhibits proliferation of HeLa, Caco-2, A549, A375, U87MG, and HL-60 cancer cells (IC50s = 1.8, 1.8, 3, 2.8, 2.3, and 1.2 µM, respectively) but not PC3 or HT-29 cancer cells (IC50s = >10 µM for both)....
Keywords: | N-(5-nitro-2-thiazolyl)-4-(trifluoromethyl)-benzamide |
Application: | STAT3 inhibitor |
CAS | 1245814-52-1 |
MW: | 317.2 D |
From 77.00€
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Item number: Cay10784-100
Peptidyl arginine deiminase 1 (PAD1) is a calcium-dependent enzyme that catalyzes the conversion of arginine residues to citrulline within its cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It exists as a monomer and is composed of a...
Keywords: | PAD1, PADI1, Peptidylarginine deiminase I, Peptidylarginine deiminase I, Protein-arginine deiminase type-1,... |
Application: | Enzyme kinetics |
MW: | 76,4 kD |
642.00€
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Item number: Cay10007884-1
Application: | Kit component |
102.00€
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