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Diethylstilbestrol
Diethylstilbestrol

Item number: Cay10006876-25

Diethylstilbestrol (DES) is a synthetic estrogen receptor agonist that was prescribed to pregnant women in the late 1930s. It was banned in 1971 because of possible links to increased risk of breast cancer in mothers along with congenital abnormalities and increased risk of cancer in offspring. DES is structurally...
Keywords: 4,4'[(1E)-1,2-diethyl-1,2-ethenediyl]bis-phenol
Application: Synthetic estrogen receptor agonist
CAS 56-53-1
MW: 268.4 D
From 35.00€ *
Review
LH 846
LH 846

Item number: Cay17686-25

LH 846 is a benzothiazole analog that selectively inhibits casein kinase (CK) 1delta (IC50 = 290 nM). It inhibits CK1epsilon and CK1alpha at much higher concentrations (IC50s = 1.3 and 2.5 µM, respectively) but does not inhibit CK2. LH 846 has been shown to inhibit CK1delta-dependent phosphorylation and degradation...
Keywords: N-(5-chloro-6-methyl-2-benzothiazolyl)-benzeneacetamide
Application: CSNK1D inhibitor
CAS 639052-78-1
MW: 316.8 D
From 43.00€ *
Review
Acetyl Podocarpic Acid Anhydride
Acetyl Podocarpic Acid Anhydride

Item number: Cay10007686-5

The liver X receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands are oxysterols. Acetyl podocarpic acid anhydride (APD) is a potent, semisynthetic LXR agonist derived from extracts of the mayapple. APD acting through LXR in concert with the retinoid X receptor (RXR), its...
Keywords: Acetylpodocarpic dimer, APD, 6-(acetyloxy)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-1-phenanthrenecarboxylic acid,...
Application: LXR agonist
CAS 344327-48-6
MW: 614.8 D
From 31.00€ *
Review