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Item number: Cay17684-25

Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 in which a switch from valine to phenylalanine occurs at the 617 position (V617F)....

Keywords:	Janus-Associated Kinase Inhibitor V, NSC 42834, Z3, 2-methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone
Application:	JAK2 inhibitor
CAS	195371-52-9
MW:	344.5 D

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