3 products were found matching "Cay10007663"!

No results were found for the filter!
Anti-SREBP-2
Anti-SREBP-2

Item number: Cay10007663-1

SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors that play a critical role in lipid homeostasis by regulating genes involved in cholesterol and fatty acid metabolism. SREBP-2 regulates cholesterol synthesis by activating the transcription...
Keywords: Anti-BHLHD2, Anti-bHLHd2, Anti-SREBP-2 {ECO:0000303|PubMed:15461802}, Anti-Class D basic helix-loop-helix protein 2,...
Application: ICC, IHC, WB
Host: Rabbit
Species reactivity: human
456.00€ *
Review
CAY10763
CAY10763

Item number: Cay30593-5

CAY10763 is a dual inhibitor of indolamine 2,3-dioxygenase 1 (IDO1, IC50 = 46 nM) and STAT3 activation. It binds to STAT3 (Kd = 530 nM) and selectively reduces the levels of STAT3 phosphorylated at the tyrosine in position 705 (STAT3Y705) over phosphorylated STAT3S727, STAT1, and STAT5 in SKOV3 cells when used at a...
Keywords: (alphaR)-alpha-[[1,4-dihydro-4-(hydroxyimino)-1-oxo-2-naphthalenyl]amino]-N-(3,5-dimethoxyphenyl)-benzenepropanamide
Application: IDO1 / STAT3 activation dual inhibitor
CAS 2364458-49-9
MW: 471.5 D
From 109.00€ *
Review
PtdIns-(3,5)-P2 (1,2-dioctanoyl) (sodium salt)
PtdIns-(3,5)-P2 (1,2-dioctanoyl) (sodium salt)

Item number: Cay10007763-100

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,5)-P2 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty...
Keywords: DOPI-3,5-P2, Phosphatidylinositol-3,5-bisphosphate C-8, 1-(1,2-dioctanoylphosphatidyl)inositol-3,5-bisphosphate, trisodium...
Application: Bioactive lipid assays
MW: 812.5 D
From 68.00€ *
Review