- Search results for Cay10007621-%25
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5 products were found matching "Cay10007621-%25"!
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Item number: Cay10008671-25
Sildenafil is a potent inhibitor of phosphodiesterase 5 (PDE5) with IC50 values of 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively. It is selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 µM, respectively). Sildenafil reverses glucose-induced decreases...
Keywords: | 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one |
Application: | PDE5 inhibitor |
CAS | 139755-83-2 |
MW: | 474.6 D |
From 64.00€
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Item number: Cay10007166-25
Leukotriene E4 (LTE4) is produced by the action of a dipeptidase on LTD4 leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
Keywords: | LTE4 methyl ester, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, methyl ester |
Application: | Bioactive lipid assays |
MW: | 453.6 D |
From 193.00€
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Item number: Cay10007461-25
Glutathione (GSH) is a tripeptide (gamma-glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of...
Keywords: | GSH, L-gamma-glutamyl-L-cysteinyl-glycine |
Application: | GST substrate |
CAS | 70-18-8 |
MW: | 307.3 D |
From 26.00€
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Item number: Cay10006217-25
Renin is an aspartyl protease glycoprotein, a member of the aspartic acid protease family, and a hormone. It is a single-chain polypeptide in which the N- and C-terminal portions contain an aspartate residue responsible for its catalytic activity. It is formed from prorenin, a zymogen found primarily in the...
Keywords: | REN, Renin, Renin, Angiotensinogenase, Angiotensinogenase |
Application: | Enzyme activity, WB |
514.00€
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Item number: Cay10004176-25
Apoptosis activator 2 promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome, thus increasing procaspase-9 processing and subsequent caspase-3 activation. This compound has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 µM) with weak or no effect on normal cell lines...
Keywords: | AAII, N-(3,4-dichlorobenzyl) Isatin, 1-[(3,4-dichlorophenyl)methyl]-1H-indole-2,3-dione |
Application: | Cell-permeable caspase activator, Apaf-1 oligomerization |
CAS | 79183-19-0 |
MW: | 306.1 D |
From 48.00€
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