- Search results for Cay10007610
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10 products were found matching "Cay10007610"!
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Item number: Cay10007766-100
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators...
Keywords: | 19S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 115461-40-0 |
MW: | 320.5 D |
From 196.00€
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Item number: Cay10007602-10
Delta2-cis Eicosenoic acid is an alpha,beta-unsaturated fatty acid that has been extracted from fresh water clams and purified. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats. Delta2-cis Eicosenoic acid and its salts...
Keywords: | 2Z-eicosenoic acid |
Application: | Bioactive lipid assays |
CAS | 93772-82-8 |
MW: | 310.5 D |
From 63.00€
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Item number: Cay10007697-10
Several different fatty acyl dopamine analogs, such as N-arachidonoyl dopamine (NADA), N-oleoyl dopamine (ODA) and N-palmitoyl dopamine (PALDA), have been isolated and characterized from bovine brain. Structurally, PALDA is the amide of palmitic acid and dopamine and is therefore a "hybrid" analog which incorporates...
Keywords: | PALDA, N-[2-(3,4-dihydroxyphenyl)ethyl]-hexadecanamide |
Application: | Bioactive lipid assays |
CAS | 136181-87-8 |
MW: | 391.6 D |
From 65.00€
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Item number: Cay10007692-10
Cross-talk between lipoxygenase (LO) and cyclooxygenase (COX) pathways has been observed in human osteoarthritic synovial explants which creates an arachidonic acid shunting phenomenon, stimulating interleukin-1beta (IL-1beta) synthesis. Licofelone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LO)...
Keywords: | ML 3000, 6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic acid |
Application: | COX inhibitor, LO inhibitor |
CAS | 156897-06-2 |
MW: | 379.9 D |
From 74.00€
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Item number: Cay10007653-10
Rho-associated kinase (ROCK), activated by GTP-linked Rho, phosphorylates targets that are involved in cytoskeletal remodeling, smooth muscle contraction, and neuronal development. H-1152 is a potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM). It is a more potent inhibitor of ROCK...
Keywords: | 5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methyl-isoquinoline, dihydrochloride |
Application: | ROCK inhibition |
CAS | 451462-58-1 |
MW: | 392.3 D |
From 48.00€
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Item number: Cay10007622-10
Delta2-trans Eicosenoic acid is an alpha,beta-unsaturated fatty acid that is a bi-product of the synthesis of Delta2-cis eicosenoic acid. Delta2-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown...
Keywords: | 2E-eicosenoic acid |
Application: | Bioactive lipid assays |
CAS | 2127095-72-9 |
MW: | 310.5 D |
From 74.00€
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Item number: Cay10007601-10
Cholesterol is the most abundant neutral lipid present in the surfactant of the lung epithelial lining fluid. The double bond between carbons 5 and 6 of cholesterol is susceptible to attack by ozone within this surfactant environment. 5alpha-hydroxy-6-keto Cholesterol (6-oxo-3,5,-diol) is a major metabolite of...
Keywords: | 6-Oxo-3,5-diol, Cholestane-6-oxo-3beta,5alpha-diol, 3beta,5alpha-dihydroxy-cholestan-6-one |
Application: | Cholesterol synthesis inhibitor |
CAS | 13027-33-3 |
MW: | 418.7 D |
From 43.00€
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Item number: Cay10007662-10
L-Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs)....
Keywords: | L-erythro-Biopterin, NSC 339699, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone |
Application: | NOS cofactor |
CAS | 22150-76-1 |
MW: | 237.2 D |
From 53.00€
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Item number: Cay10007686-10
The liver X receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands are oxysterols. Acetyl podocarpic acid anhydride (APD) is a potent, semisynthetic LXR agonist derived from extracts of the mayapple. APD acting through LXR in concert with the retinoid X receptor (RXR), its...
Keywords: | Acetylpodocarpic dimer, APD, 6-(acetyloxy)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-1-phenanthrenecarboxylic acid,... |
Application: | LXR agonist |
CAS | 344327-48-6 |
MW: | 614.8 D |
From 31.00€
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Item number: Cay10007691-10
URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 µM. There is evidence that the MAGL inhibitory...
Keywords: | 6-methyl-2-[(4-methylphenyl)amino]-1-benzoxazin-4-one |
Application: | Potent noncompetitive monoglyceride lipase (MGL) inhibitor |
CAS | 86672-58-4 |
MW: | 266.3 D |
From 48.00€
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