10 products were found matching "Cay10007274"!

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...

Prostaglandin E2-d4 (PGE2-d4) is intended for use as an internal standard for the quantification of PGE2 (Cay-14010) by GC- or LC-MS. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation,...

Arachidonoyl ethanolamide (AEA) is the ethanolamine amide of arachidonic acid (Cay-90010), first isolated from porcine brain. AEA is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. AEA inhibits the specific binding of [3H]-HU-243 to...

FK-506 is a potent immunosuppressant that forms a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation. Synthetic ligand of FKBP (SLF) is a...

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N-methyl amide is an analog of...

Epoxyeicosatrienoic acid (EpETrE) metabolites of arachidonic acid such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding dihydroxy eicosatrienoic...

p38 is a member of the mitogen-activated protein kinase (MAPK) superfamily of enzymes that play an important role in signal transduction. PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK)...

Several different arachidonoyl amino acid conjugates, including N-arachidonoyl dopamine and N-arachidonoyl-L-serine, have been isolated and characterized from bovine brain. N-Nervonyl taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of brain and...

5-Chloroesorcinol dimethyl ether is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 1-chloro-3,5-dimethoxy-benzene. CAS Number: 7051-16-3. Synonyms: NSC 220095. Molecular Formula: C8H9ClO2. Formula Weight: 172.6. Purity: >98%. Formulation: (Request formulation change), A liquid. Solubility:...