- Search results for Cay10007222
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4 products were found matching "Cay10007222"!
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Item number: Cay22404-10
CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 µM). SIRT3 is involved in modulating metabolic homeostasis as a NAD+-dependent protein deacetylase in the mitochondria. SIRT3 functions as either an oncogene or tumor suppressor, depending on cancer cell type. High SIRT3...
Keywords: | N-[2-(2,4-dichlorophenyl)-5-benzoxazolyl]-benzeneacetamide |
Application: | SIRT3 inhibitor |
CAS | 388086-13-3 |
MW: | 397.3 D |
From 43.00€
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Item number: Cay10072-250
Ursolic acid is a pentacyclic triterpenoid that has been isolated from M. pumila and has diverse biological activities, including anticancer, hepatoprotective, anti-inflammatory, antioxidant, antimicrobial, and cardioprotective properties. It inhibits the proliferation of HepG2 liver, MCF-7 breast, and Caco-2 colon...
Keywords: | Bungeolic Acid, Maerotaine, Malol, NSC 167406, NSC 4060, Prunol, 3beta-hydroxy-urs-12-en-28-oic acid |
Application: | Na/K-ATPase inhibitor |
CAS | 77-52-1 |
MW: | 456.7 D |
From 44.00€
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Item number: Cay10722-25
JWH 302 (Cay-10722) is a cannabimimetic indole that shows 5-fold selectivity for the central cannabinoid (CB1) receptor with a Ki value of 17 nM compared to the peripheral cannabinoid (CB2) receptor (Ki = 89 nM). JWH 302 stimulates GTPgammaS binding of CB1 and CB2 receptors with EC50 values of 29.3 and 24.4 nM,...
Keywords: | 2-(3-methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone |
Application: | Analytical reference standard, cannabimimetic indole |
CAS | 864445-45-4 |
MW: | 335.4 D |
From 276.00€
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Item number: Cay11072-5
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 µM, bisindolylmaleimide III inhibits 93% of PKCalpha kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-K1, RSK2 and MSK1 with...
Keywords: | BIM III, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor |
CAS | 137592-43-9 |
MW: | 384.4 D |
From 77.00€
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