JWH 073 7-hydroxyindole metabolite-d7 contains seven deuterium atoms at the 2, 2', 3, 3', 4, 4, and 4 positions. It is intended for use as an internal standard for the quantification of JWH 073 7-hydroxyindole metabolite by GC- or LC-mass spectrometry (MS). JWH 073 is a mildly selective agonist of the central...

GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance...

To be used in conjunction with Cayman's GPR40 polyclonal antibody (Catalog No. 10007605) to block protein-antibody complex formation during immunochemical analysis of GPR40.Amino Acids: human GPR40 amino acids 210-222. Formulation: (Request formulation change), 200 µg of peptide in 200 µl PBS, pH 7.2, containing...

Adiponectin, (Acrp30, AdipoQ, GBP-28), is a 244 amino acid protein specifically and highly expressed by adipose cells. Expression of adiponectin is inversely related to the degree of adiposity in which a reduction in serum adiponectin levels are accompanied by an increase in insulin resistance states, such as...

The enzyme 5-lipoxygenase (5-LO) plays a key role in regulating the production of leukotrienes (LTs). Overproduction of LTs contributes to several diseases, most notably chronic inflammatory diseases such as asthma, fibrosis, and atherosclerosis. Recent work has demonstrated that the activity of 5-LO is regulated by...