Microcystin-LA is a cyanotoxin and an inhibitor of protein phosphatase 1C (PP1C) and PP2A (IC50 = 0.3 nM for both). In vivo, microcystin-LA (7 mg/kg) induces moribundity and increases liver-to-body weight ratios and serum levels of alanine transaminase (ALT), aspartate aminotransferase (AST), and glutamate...

R-(-)-Mandelic Acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: alphaR-hydroxy-benzeneacetic acid. CAS Number: 611-71-2. Synonyms: D-(-)-Mandelic Acid. Molecular Formula: C8H8O3. Formula Weight: 152.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid....

Dimethylcurcumin is a selective enhancer of androgen receptor (AR) degradation. By disrupting the interaction between AR and its coregulators, dimethylcurcumin directs the degradation of AR and reduces signaling through this receptor both in cultured cells and in animals. In this way, dimethylcurcumin suppresses the...

DAUDA is an environment-sensitive fluorescent fatty acid analogue that alters its fluorescent emission spectra and intensities on entry into binding proteins. DAUDA has been used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein by...