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2-deoxy-2-fluoro L-Fucose
2-deoxy-2-fluoro L-Fucose

Item number: Cay17171-25

2-deoxy-2-fluoro L-Fucose is a fluorinated fucose analog. It can be metabolized inside the cell to a substrate-based inhibitor of fucosyltransferases. Alternatively, it can be converted in vitro to GDP-2-deoxy-2-fluoro L-fucose, a competitive inhibitor of alpha1,3-fucosyltransferase V (Ki = 4.2 µM).Formal Name:...
Keywords: 2,6-dideoxy-2-fluoro-L-galactose
Application: Fucosyltransferase inhibitor
CAS 70763-62-1
MW: 166.1 D
From 60.00€ *
Review
GSK650394
GSK650394

Item number: Cay17001-25

GSK650394 is an inhibitor of serum- and glucocorticoid-regulated kinase (IC50s = 62 and 103 nM for SGK1 and SGK2, respectively). It demonstrates greater than 30-fold selectivity for SGK1 over Akt and other related kinases. GSK650394 can inhibit the androgen-stimulated growth of human prostate carcinoma LNCaP cells...
Keywords: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-benzoic acid
Application: SGK1/2 inhibitor
CAS 890842-28-1
MW: 382.5 D
From 142.00€ *
Review
AP219
AP219

Item number: Cay17101-25

AP39 (Cay-17100) is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219 is a control compound for AP39, containing the...
Keywords: (9-carboxynonyl)triphenyl-phosphonium
Application: AP39 control
CAS 779282-36-9
MW: 433.6 D
From 43.00€ *
Review