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COVID-19 Research
E-64c
E-64c

Item number: Cay10007964-25

E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: Loxistatin Acid, NSC 694279,...
Application: Cysteine protease inhibitor
CAS 76684-89-4
MW: 314.4 D
From 84.00€ *
Review
Ionomycin
Ionomycin

Item number: Cay10004974-5

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 60.00€ *
Review
Leptomycin B
Leptomycin B

Item number: Cay10004976-25

Leptomycin B is a potent inhibitor of the nuclear export of proteins. It directly blocks the interaction of CRM1 (exportin 1) with nuclear export signals (NES), preventing the export of a broad range of proteins. Leptomycin B will also indirectly inhibit the export of mRNA from the nucleus by blocking the nuclear...
Keywords: Elactocin, LMB, Mantuamycin, NSC 364372,...
Application: Nuclear export blocker
CAS 87081-35-4
MW: 540.7 D
From 48.00€ *
Review