3 products were found matching "Cay10006748-%25"!
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GW 0742
Item number: Cay10006798-25
The transcription factor peroxisome proliferator-activated receptor delta (PPARdelta) is a member of the superfamily of nuclear hormone receptors and is implicated both in lipid metabolism and in the regulation of genes with potential roles in neurotoxicity. GW 0742 is a selective PPARdelta agonist (EC50 = 1.1 nM)...
| Keywords: | GW 610742, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-acetic acid |
| Application: | PPARdelta agonist |
| CAS | 317318-84-6 |
| MW: | 471.5 D |
From 109.00€
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Leelamine
Item number: Cay10006148-25
Leelamine is a diterpene amine that has been found in gum resin and has diverse biological activities. It inhibits pyruvate dehydrogenase kinase (PDHK, IC50 = 9.5 µM). Leelamine is active against the plant pathogenic fungus B. cinerea (EC50 = 70 µM). It induces apoptosis in UACC-903 and 1205Lu melanoma cell lines...
| Keywords: | Dehydroabietylamine, 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine |
| Application: | PDK inhibitor |
| CAS | 1446-61-3 |
| MW: | 285.5 D |
From 50.00€
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CAY10486
Item number: Cay10006452-25
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of...
| Keywords: | 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide, N-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-L-phenylalanine,... |
| Application: | ACAT-1 / ACAT-2 inhibitor |
| CAS | 615264-52-3 |
| MW: | 325.4 D |
From 40.00€
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