- Search results for Cay10006726-%25
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10 products were found matching "Cay10006726-%25"!
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Item number: Cay10007766-25
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators...
Keywords: | 19S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 115461-40-0 |
MW: | 320.5 D |
From 196.00€
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Item number: Cay10006727-25
p38 is a member of the mitogen-activated protein kinase (MAPK) superfamily of enzymes that play an important role in signal transduction. PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK)...
Keywords: | 4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl]-pyridine |
Application: | p38 MAPK inhibitor |
CAS | 152121-53-4 |
MW: | 360.3 D |
From 84.00€
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Item number: Cay10006627-25
Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid...
Keywords: | C16:0, hexadecanoic acid |
Application: | Bioactive lipid assays |
CAS | 57-10-3 |
MW: | 256.4 D |
From 43.00€
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Item number: Cay10006967-25
Zileuton is a reversible 5-lipoxygenase (5-LO) inhibitor. It inhibits 5-LO activity in rat basophilic leukemia-1 (RBL-1) cell supernatant with an IC50 value of 0.5 µM. Zileuton inhibits leukotriene B4 (LTB4, Cay-20110) production induced by the calcium ionophore A23187 (Cay-11016) in purified human peripheral blood...
Keywords: | A 64077, N-(1-benzo[b]thien-2-ylethyl)-N-hydroxy-urea |
Application: | 5-LO inhibitor |
CAS | 111406-87-2 |
MW: | 236.3 D |
From 28.00€
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Item number: Cay10006607-25
Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free...
Keywords: | Sodium Arachidonate, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, monosodium salt |
Application: | Bioactive lipid assays |
CAS | 6610-25-9 |
MW: | 326.5 D |
From 68.00€
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Item number: Cay10006876-25
Diethylstilbestrol (DES) is a synthetic estrogen receptor agonist that was prescribed to pregnant women in the late 1930s. It was banned in 1971 because of possible links to increased risk of breast cancer in mothers along with congenital abnormalities and increased risk of cancer in offspring. DES is structurally...
Keywords: | 4,4'[(1E)-1,2-diethyl-1,2-ethenediyl]bis-phenol |
Application: | Synthetic estrogen receptor agonist |
CAS | 56-53-1 |
MW: | 268.4 D |
From 35.00€
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Item number: Cay10007166-25
Leukotriene E4 (LTE4) is produced by the action of a dipeptidase on LTD4 leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
Keywords: | LTE4 methyl ester, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, methyl ester |
Application: | Bioactive lipid assays |
MW: | 453.6 D |
From 193.00€
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Item number: Cay10006626-25
Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil. Lauric acid induces the activation of NF-kappaB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1alpha in RAW 264.7 cells when used at a concentration of 25 µM.Formal Name: dodecanoic...
Keywords: | C12:0, Dodecanoic Acid, NSC 5026, dodecanoic acid |
Application: | Lipid assays |
CAS | 143-07-7 |
MW: | 200.3 D |
20.00€
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Item number: Cay10009667-25
all-cis-1,2,3-Docosahexaenoyl glycerol is a polyunsaturated triacylglycerol that contains all-cis docosahexaenoic acid (DHA, Cay-90310) at the sn-1, sn-2, and sn-3 positions.Formal Name: (4Z,4'Z,4''Z,7Z,7'Z,7''Z,10Z,10'Z,10''Z,13Z,13'Z,13''Z,16Z,16'Z,16''Z,19Z,19'Z,19''Z)-4,7,10,13,16,19-docosahexaenoic acid,...
Keywords: | all-cis-1,2,3-Docosahexaenoyl-rac-glycerol, all-cis-Glycerol Tridocosahexaenoate, all-cis-Tridocosahexaenoic Acid,... |
CAS | 124596-98-1 |
MW: | 1023.5 D |
From 43.00€
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Item number: Cay10006326-25
Procysteine is a prodrug form of cysteine that is metabolized to cysteine intracellularly and has antioxidant activity. It reduces TNF-alpha-induced increases in the expression of IL-6 and chemokine (C-C motif) ligand 2 (CCL2) in ARPE-19 human retinal pigment epithelial cells when used at a concentration of 0.5 mM....
Keywords: | L-2-oxothiazolidine-4-carboxylate, L-2-oxothiazolidine-4-carboxylic acid, OTC, 2-oxo-(4R)-4-thiazolidinecarboxylic acid |
Application: | Cysteine prodrug, Antioxidant |
CAS | 19771-63-2 |
MW: | 147.2 D |
From 60.00€
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