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Item number: Cay10006726-1

PD 98059 is a noncompetitive inhibitor of the MAPK pathway. It prevents the activation of MEK by Raf or MEK kinase (a MAP3K) with an IC50 value of 2-7 µM but does not inhibit Raf-activated MAP2K1. It inhibits Raf activation of MAP2K2 with an IC50 value of 50 µM. PD 98059 also phosphorylates and activates...

Keywords:	NSC 679828, 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
Application:	MAPK inhibitor
CAS	167869-21-8
MW:	267.3 D

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