6 products were found matching "Cay10006695"!

Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase activity. HEPC is a truncated analog of phosphatidylcholine with the entire sn-1 substituent deleted, and with a hexadecylthioester in the sn-2 position. HEPC...

Adipocyte fatty acid binding protein (A-FABP/aP2) is a carrier protein expressed in both adipocytes and macrophages where it functions in intracellular fatty acid solubilization, trafficking, and metabolism. Molecular disruption of A-FABP/aP2 in mice results in improved insulin sensitivity and protection from...

Phytoenoic and phytodienoic acids are cyclopentenone oxylipins biosynthesized in plants from linoleic acid (Cay-90150). Cyclopentenones are converted to cyclopentanones by reductases, as occurs in the jasmonic acid pathway. CAY10695 is a 14-carbon cyclopentanone that is structurally related to a variety of plant...

Nitric Oxide (NO) is a free radical gas that is involved in a variety of biological processes including regulation vascular tone, neuronal signaling, and host defense. Nitroxyl (HNO) is the one electron reduced form of nitric oxide. Piloty's acid is one of the best known and most widely used HNO donors. Under basic...

Cloprostenol is a synthetic prostaglandin F2alpha (PGF2alpha) analog and a potent FP receptor agonist. (+)-15-epi Cloprostenol is the 15(S), or 15beta-hydroxy enantiomer of (+)-cloprostenol. This epimer is less active by several orders of magnitude as an FP receptor ligand when compared to 15(R)-cloprostenol....

Central cannabinoid (CB1) receptor antagonists and inverse agonists exhibit therapeutic potential for obesity and drug dependence, while being devoid of psychotropic effects. CAY10508 is a potent and selective central cannabinoid (CB1) receptor inverse agonist with a Ki value of 243 nM and an EC50 of 195 nM. A 10 µM...