- Search results for Cay10006595-%25
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5 products were found matching "Cay10006595-%25"!
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Item number: Cay10006545-25
The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin (TCDD, 2,3,7,8-tetrachlorodibenzoparadioxin), benzo[a]pyrene, and numerous polyaromatic hydrocarbons from soot particles and coal tar. CAY10464 is...
Keywords: | 1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene |
Application: | AhR antagonist |
CAS | 688348-37-0 |
MW: | 279.2 D |
From 30.00€
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Item number: Cay10008596-25
Arachidonyl ethanolamide (AEA, Cay-90050) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism...
Keywords: | (±)5,6-EpETrE Ethanolamide, N-(2-hydroxyethyl)-(±)5,6-epoxy-8Z,11Z,14Z-eicosatrienamide |
Application: | Bioactive lipid assays |
MW: | 363.5 D |
From 119.00€
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Item number: Cay10009965-25
VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN, IC50 = 35 nM in vitro). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular...
Keywords: | (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxo-v... |
Application: | PTEN inhibitor |
CAS | 476310-60-8 |
MW: | 415.2 D |
From 44.00€
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Item number: Cay10006695-25
Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase activity. HEPC is a truncated analog of phosphatidylcholine with the entire sn-1 substituent deleted, and with a hexadecylthioester in the sn-2 position. HEPC...
Keywords: | 2-Hexadecanoylthio-1-Ethylphosphorylcholine,... |
Application: | Bioactive lipid assays |
CAS | 60793-01-3 |
MW: | 481.7 D |
From 211.00€
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Item number: Cay10009078-25
Phosphoinositide 3-kinase gamma (PI3Kgamma), expressed primarily in hematopoietic cells, plays several important roles in immunity. CAY10505 is a potent inhibitor of PI3K, selectively inhibiting the gamma isoform (IC50 = 30 nM) better than the alpha, beta, and delta isoforms (IC50 = 0.94, 20, and 20 µM,...
Keywords: | 5-[[5-(4-fluorophenyl)-2-furanyl]methylene]-2,4-thiazolidinedione |
Application: | PI3K inhibitor |
CAS | 328960-84-5 |
MW: | 289.3 D |
From 50.00€
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