- Search results for Cay10006485
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5 products were found matching "Cay10006485"!
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Item number: Cay10006485-500
Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of...
Keywords: | E1, 3-hydroxy-estra-1,3,5(10)-trien-17-one |
Application: | Bioactive lipid assays |
CAS | 53-16-7 |
MW: | 270.4 D |
16.00€
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Item number: Cay10006482-5
Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 values of 95 and 81 µM,...
Keywords: | 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide,... |
Application: | acylCoA inhibitor |
CAS | 615264-62-5 |
MW: | 477.5 D |
From 48.00€
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Item number: Cay10006480-5
The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting...
Keywords: | 3,4-Dihydrocinnamic Acid (L-alanine methyl ester) amide, N-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-L-alanine,... |
Application: | Metabolic studies, Antioxidant |
CAS | 778624-05-8 |
MW: | 265.3 D |
From 39.00€
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Item number: Cay10006408-5
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinases in vivo, and then acts as a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720...
Keywords: | (S)-FTY 720P, (2S)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol |
Application: | Metabolic studies |
CAS | 402616-26-6 |
MW: | 387.5 D |
From 94.00€
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Item number: Cay10006148-5
Leelamine is a diterpene amine that has been found in gum resin and has diverse biological activities. It inhibits pyruvate dehydrogenase kinase (PDHK, IC50 = 9.5 µM). Leelamine is active against the plant pathogenic fungus B. cinerea (EC50 = 70 µM). It induces apoptosis in UACC-903 and 1205Lu melanoma cell lines...
Keywords: | Dehydroabietylamine, 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine |
Application: | PDK inhibitor |
CAS | 1446-61-3 |
MW: | 285.5 D |
From 50.00€
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