20 products were found matching "Cay10006400"!
No results were found for the filter!
CAY10462
Item number: Cay10006400-10
20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. Alkylaryl imidazoles have been shown to inhibit certain CYP450 enzymes, including the CYP4A enzymes associated with 20-HETE synthesis....
| Keywords: | 6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine, dihydrochloride |
| Application: | CYP4A11 inhibitor |
| CAS | 502656-68-0 |
| MW: | 360.3 D |
From 34.00€
*
CAY10640
Item number: Cay10642-1
Soluble epoxide hydrolase (sEH) inhibitors have important therapeutic use by increasing the in vivo concentration of EETs and other fatty acid epoxides, resulting in anti-inflammatory, antihypertensive, neuroprotective, and cardioprotective effects. CAY10640 is a 1-aryl-3-(1-acylpiperidin-4-yl)urea analog that...
| Keywords: | sEHi, Soluble Epoxide Hydrolase Inhibitor, N-[1-(cyclopropylcarbonyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl]-urea |
| Application: | Soluble epoxide hydrolase (sEH) inhibitor |
| CAS | 1208549-68-1 |
| MW: | 371.4 D |
From 73.00€
*
SEW2871
Item number: Cay10006440-10
Sphingosine-1-phosphate receptor 1 (S1P1) is one of five high affinity G protein-coupled S1P receptors which mediate a variety of effects including lymphocyte recirculation in the blood. Non-selective S1P receptor agonists, such as FTY720, produce clinical immunosuppression useful for preventing transplant rejection...
| Keywords: | 5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole |
| Application: | S1P1 receptor agonist |
| CAS | 256414-75-2 |
| MW: | 440.4 D |
From 43.00€
*
KM 233
Item number: Cay10640-25
Because selective activation of peripheral cannabinoid (CB2) receptors in rat C-6 glioma cells has been shown to induce apoptosis through enhanced ceramide synthesis de novo, CB2 agonists present potential as anti glioma agents. KM 233 is a Delta8-tetrahydrocannabinol analog with a dimethyl substitution that...
| Keywords: | 6aR,7,10,10aR-tetrahydro-6,6,9-trimethyl-3-(1-methyl-1-phenylethyl)-6H-dibenzo[b,d]pyran-1-ol |
| Application: | Dual CB1 / CB2 receptor agonist |
| CAS | 628263-22-9 |
| MW: | 362.5 D |
From 85.00€
*
Pentacosanoic Acid methyl ester
Item number: Cay10006451-100
Long chain saturated fatty acids and their esters are common components of plant lipids. Pentacosanoic acid methyl ester is the methyl ester of the 25-carbon, fully saturated fatty acid pentacosanoic acid. This product is designed to be used as a standard in total fatty acid analysis.Formal Name: pentacosanoic acid,...
| Keywords: | Methyl Pentacosanoate, pentacosanoic acid, methyl ester |
| Application: | Standard |
| CAS | 55373-89-2 |
| MW: | 396.7 D |
From 89.00€
*
DMPO
Item number: Cay10006436-500
Free radicals are highly reactive, short-lived species. Spin traps react with radicals, forming stable adducts that can be further studied. DMPO is a commonly-used spin trap that reacts with O-, N-, S-, and C-centered radicals. This allows their characterization when used in association with electron spin resonance...
| Keywords: | 5,5-Dimethyl-1-Pyrroline-N-Oxide, 3,4-dihydro-2,3-dimethyl-2H-pyrrole 1-oxide |
| Application: | Spin trap |
| CAS | 3317-61-1 |
| MW: | 113.2 D |
From 84.00€
*
FTY720 (R)-Phosphate
Item number: Cay10006407-10
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinases in vivo, and then acts as a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720...
| Keywords: | (2R)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol |
| Application: | S1P analog |
| CAS | 402616-23-3 |
| MW: | 387.5 D |
From 84.00€
*
FTY720 (S)-Phosphate
Item number: Cay10006408-10
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinases in vivo, and then acts as a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720...
| Keywords: | (S)-FTY 720P, (2S)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol |
| Application: | Metabolic studies |
| CAS | 402616-26-6 |
| MW: | 387.5 D |
From 94.00€
*
omega-3 Arachidonic Acid methyl ester
Item number: Cay10006454-500
omega-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and alpha-linoleate, are essential dietary nutrients required for normal growth and development. omega-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid omega-3 arachidonic acid. The...
| Keywords: | 8Z,11Z,14Z,17Z-eicosatetraenoic acid, methyl ester |
| Application: | Bioactive lipid assays |
| CAS | 132712-70-0 |
| MW: | 318.5 D |
From 92.00€
*
Estrone
Item number: Cay10006485-500
Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of...
| Keywords: | E1, 3-hydroxy-estra-1,3,5(10)-trien-17-one |
| Application: | Bioactive lipid assays |
| CAS | 53-16-7 |
| MW: | 270.4 D |
16.00€
*
Estriol
Item number: Cay10006484-100
Estriol is a metabolite of estradiol and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from 10 weeks gestation to approximately 150 ng/ml at week 38. The majority of the estriol synthesized in the later stages of...
| Keywords: | 1,3,5(10)-Estratriene-3,16alpha,17beta-triol, 16alpha-hydroxy-17beta-estradiol, E3,... |
| Application: | Bioactive lipid assays |
| CAS | 50-27-1 |
| MW: | 288.4 D |
From 19.00€
*
(±)14(15)-EET-d11
Item number: Cay10006410-100
(±)14(15)-EET-d11 is intended for use as an internal standard for the quantification of (±)14(15)-EET (Cay-50651) by GC- or LC-MS. 14(S),15(R)-EET and 14(R),15(S)-EET are formed via epoxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by a variety of cytochrome P450 (CYP) isoforms. 14(S),15(R)-EET...
| Keywords: | (±)14,15-EET-d11, (±)14,15-EpETrE-d11, (±)14(15)-epoxy-5Z,8Z,11Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
| Application: | Standard |
| MW: | 331.5 D |
From 245.00€
*