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D-NMAPPD
D-NMAPPD

Item number: Cay10006305-1

D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but has no effect on viability of rat hepatocytes, Kupffer cells, or sinusoidal endothelial cells when used at a concentration of 100 mM. D-NMAPPD increases intracellular...
Keywords: (1R,2R)-B13, CAY10466, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-tetradecanamide
Application: Ceramidase inhibitor
CAS 35922-06-6
MW: 422.6 D
From 39.00€ *
Review
BCTC
BCTC

Item number: Cay10006309-5

The vanilloid receptor 1 (TRPV1) is a ligand-gated ion channel highly expressed on primary nociceptive neurons that respond to a variety of noxious stimuli, including heat, acid, and other chemical irritants. Because disruptions in TRPV1 activity cause reduced thermal nociception and hyperalgesia, this receptor is...
Keywords: 4-(3-chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
Application: TRPV1 antagonist
CAS 393514-24-4
MW: 372.9 D
From 56.00€ *
Review