- Search results for Cay10006211
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10 products were found matching "Cay10006211"!
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Item number: Cay10006211-5000
Silybin is the major flavonolignan found in milk thistle (S. marianum). It inhibits wild mushroom tyrosinase (IC50 = 1.7 µM). Silybin scavenges superoxide radicals (IC50 = 55.2 µM) and inhibits lipid peroxidation in vitro (IC50 = 73.92 µM).Formal Name:...
Keywords: | (2R,3R)-2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-tri... |
Application: | Superoxide blocker |
CAS | 22888-70-6 |
MW: | 482.4 D |
From 23.00€
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Item number: Cay13371-1
CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 3.3 µM). It is selective for SPHK1 over SPHK2 at 10 µM and PKC at concentrations less than 100 µM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 µM.Formal Name:...
Keywords: | SKI 5C, SPHK1 Inhibitor 5C, (4S)-2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-3-oxazolidinecarboxylic acid, 1,1-dimethylethyl... |
Application: | SPHK 1 inhibitor |
CAS | 120005-55-2 |
MW: | 435.6 D |
From 38.00€
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Item number: Cay11062-1
2-amino Benzamidoxime is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 2-amino-N-hydroxy-benzenecarboximidamide. CAS Number: 16348-49-5. Molecular Formula: C7H9N3O. Formula Weight: 151.2. Purity: >97%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5...
Keywords: | 2-amino-N-hydroxy-benzenecarboximidamide |
Application: | Synthetic intermediate |
CAS | 16348-49-5 |
MW: | 151.2 D |
From 48.00€
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Item number: Cay10662-1
Cytosolic phospholipase A2alpha (cPLA2alpha) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process. CAY10641 is an...
Keywords: | 1-[2-hydroxy-3-(4-phenoxyphenoxy)propyl]-3-(2-methyl-1-oxopropyl)-1H-indole-5-carboxylic acid |
Application: | cPLA2alpha inhibitor |
CAS | 1233706-89-2 |
MW: | 473.5 D |
From 63.00€
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Item number: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
Keywords: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
Application: | PARP1 / PARP2 inhibitor |
CAS | 763113-22-0 |
MW: | 434.5 D |
From 66.00€
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Item number: Cay10006421-1
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcription factor that accumulates under low-oxygen conditions. Following hypoxic stimulus and cytoplasmic accumulation, HIF-1alpha migrates to the nucleus where with other transcription factors, it drives the production of stress-adaptive proteins. This response...
Keywords: | Anti-BHLHE78, Anti-bHLHe78, Anti-bHLHe78, Anti-ARNT-interacting protein, Anti-ARNT-interacting protein, Anti-PAS... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
422.00€
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Item number: Cay10006212-1
alpha-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-7 is a more lipophilic analog of alpha-lipoic acid with enhanced potency and 1.5-fold...
Keywords: | 3-(5-[1,2]dithiolan-3yl-pentanoylamino)-propyl]-amide |
Application: | Alpha-lipoic acid analog |
CAS | 691410-93-2 |
MW: | 450.7 D |
From 43.00€
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Item number: Cay10007621-1
Glial fibrillary acidic protein (GFAP) is a 40-53 kDa monomeric molecule found only in adult glial cells of the central nervous system (CNS) and represents the major part of the cytoskeleton of astrocytes. Traumatic injury to the adult CNS results in a rapid inflammatory response by the resident astrocytes,...
Keywords: | Glial Fibrillary Acidic Protein (human) ELISA Kit |
Application: | ELISA |
Species reactivity: | human |
1,342.00€
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Item number: Cay10006321-1
Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis. Three major metabolites of tibolone are responsible for its tissue selective mechanism of action. Conversion into 3alpha- and...
Keywords: | 7alpha-Methyl-Delta5,10-norethindrone, Org OD 14, 17alpha-hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one |
Application: | Estrogen receptor agonist, SERM |
CAS | 5630-53-5 |
MW: | 312.5 D |
From 46.00€
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Item number: Cay10006521-1
For use in Cayman's S-Nitrosylated Protein Detection Kit.
Application: | Kit component |
40.00€
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