7 products were found matching "Cay10005726"!

PD 98059 is a noncompetitive inhibitor of the MAPK pathway. It prevents the activation of MEK by Raf or MEK kinase (a MAP3K) with an IC50 value of 2-7 µM but does not inhibit Raf-activated MAP2K1. It inhibits Raf activation of MAP2K2 with an IC50 value of 50 µM. PD 98059 also phosphorylates and activates...

The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation. Arachidoyl...

Sterol O-acyltransferase 2 (SOAT-2), also known as acyl-coenzyme A:cholesterol acyltransferase-2 (ACAT-2), is an enzyme encoded by ACAT2 in humans that catalyzes the intracellular formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A. It is constitutively expressed in the liver and...

DL-alpha-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle, and acts as a general antioxidant. DL-alpha-lipoic acid can act as a direct radical scavenger, as a cofactor to regenerate...

To be used in conjunction with Cayman's 11beta-HSD1 Polyclonal Antibody (Cay-10004303) to block protein-antibody complex formation during immunochemical analysis of 11beta-HSD1.Synonyms: 11beta-HSD1, Corticosteroid 11beta-Dehydrogenase Isozyme 1. Amino Acids: Human 11beta-HSD1 amino acids 78-92 (CLELGAASAHYLAGT)....

Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase alpha (DAGLalpha), DAGLbeta, alpha/beta-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH, IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase...

DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP (Cay-62595): D-threo-(1R,2R)-PDMP and L-threo-(1S,2S)-PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 µM. It reduces the...