The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation. Arachidoyl...

Cytohesins are small guanine nucleotide exchange factors (GEFs) that stimulate adenosine diphosphate ribosylation factors (Arfs), GTPases which control signal transduction along various intracellular pathways. SecinH3 is a selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50...

Molecules having vitamin E antioxidant activity include four tocopherols (alpha, beta, delta, and gamma) and four tocotrienols (alpha, beta, delta, and gamma). alpha-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation. alpha-CEHC is the major urinary metabolite of...