- Search results for Cay10005705
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4 products were found matching "Cay10005705"!
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Item number: Cay10005705-5
NO-indomethacin is a hybrid molecule of indomethacin and a nitric oxide (NO) donor. This drug design combines the anti-inflammatory properties of a non-steroidal anti-inflammatory drug (NSAID) with the gastrointestinal protective effects of NO. Compounds of this class retain their anti-inflammatory and analgesic...
Keywords: | NCX 2121, N-acetyl-D-cysteine-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 4-(nitrooxy)butyl ester |
Application: | NO donor |
CAS | 301838-28-8 |
MW: | 620.1 D |
From 28.00€
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Item number: Cay10005707-5
Lysophosphatidic acid (LPA) is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23. OMPT is a selective agonist of the lysophosphatidic acid 3 (LPA3) receptor. It exhibits EC50 values of 68 nM and >6.8 µM for calcium mobilization in LPA1...
Keywords: | 9Z-octadecenoic acid, (2S)-3-[(hydroxymercaptophosphinyl)oxy]-2-methoxypropyl ester, triethyl ammonium salt (1:2) |
Application: | LPA3 receptor agonist |
CAS | 1217471-69-6 |
MW: | 669 D |
From 96.00€
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Item number: Cay10005270-5
Inhibition of fatty acid synthase (FASN) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines. (±)-C75 is a stable inhibitor of FASN that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice....
Keywords: | tetrahydro-4-methylene-2R-octyl-5-oxo-3S-furancarboxylic acid |
Application: | FAS inhibitor |
CAS | 191282-48-1 |
MW: | 254.3 D |
From 60.00€
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Item number: Cay10009570-5
Cytohesins are small guanine nucleotide exchange factors (GEFs) that stimulate adenosine diphosphate ribosylation factors (Arfs), GTPases which control signal transduction along various intracellular pathways. SecinH3 is a selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50...
Keywords: | N-[4-[5-(1,3-benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)-acetamide |
Application: | Selective cytohesin inhibitor |
CAS | 853625-60-2 |
MW: | 460.5 D |
From 66.00€
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