3 products were found matching "Cay10005270"!

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(±)-C75
(±)-C75

Item number: Cay10005270-1

Inhibition of fatty acid synthase (FASN) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines. (±)-C75 is a stable inhibitor of FASN that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice....
Keywords: tetrahydro-4-methylene-2R-octyl-5-oxo-3S-furancarboxylic acid
Application: FAS inhibitor
CAS 191282-48-1
MW: 254.3 D
From 60.00€ *
Review
DL-threo-PDMP (hydrochloride)
DL-threo-PDMP (hydrochloride)

Item number: Cay10005276-50

DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP (Cay-62595): D-threo-(1R,2R)-PDMP and L-threo-(1S,2S)-PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 µM. It reduces the...
Keywords: N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride
Application: Bioactive lipid assays
CAS 80938-69-8
MW: 427 D
From 85.00€ *
Review
(-)-L-threo-PDMP (hydrochloride)
(-)-L-threo-PDMP (hydrochloride)

Item number: Cay10005278-10

(-)-L-threo-PDMP is a ceramide analog and one of the four possible stereoisomers of PDMP (Cay-62595). L-threo-PDMP is an enhancer of ganglioside biosynthesis. It increases glucosylceramide synthase activity by 4 and 8% when used at concentrations of 5 and 2.5 µM, respectively, in an enzyme assay. L-threo-PDMP...
Keywords: N-[(1S,2S)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride
Application: Ganglioside biosynthesis enhancer
CAS 161491-04-9
MW: 427 D
From 88.00€ *
Review