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Item number: Cay10523-25

Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 µM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 µM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and...

Keywords:	Sir Two Inhibitor Naphthol, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)-benzamide
Application:	Sirtuin inhibitor
CAS	410536-97-9
MW:	394.5 D

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