- Search results for Cay10005198
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10 products were found matching "Cay10005198"!
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Item number: Cay10005189-5
PX-478 suppresses both constitutive and hypoxia-induced levels of HIF-1alpha in cancer cells, resulting in reduced expression of HIF-1alpha target genes. It induces apoptosis in human tumor xenografts in mice to an extent that is proportional to initial HIF-1alpha level. PX-478 can also increase chemo- or...
Keywords: | 4-[bis(2-chloroethyl)oxidoamino]-L-phenylalanine, dihydrochloride |
Application: | HIF-1 alpha inhibitor |
CAS | 685898-44-6 |
MW: | 394.1 D |
From 89.00€
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Item number: Cay10008519-5
CYP3A4 and CYP3A5 are cytochrome P450 enzymes whose expression is induced by glucocorticoids and certain xenobiotics, including many drugs and chemical carcinogens. They mediate the metabolism of xenobiotics as well as certain endobiotics, including steroid hormones. CYP3A4 and CYP3A5 are cytochrome P450 enzymes...
Keywords: | 4-Androsten-6beta,17beta-diol-3-one, 6beta, 17beta,-Dihydroxyandrost-4-en-3-one, 6beta,17beta-androst-4-en-3-one |
Application: | Bioactive lipid assays |
CAS | 62-99-7 |
MW: | 304.4 D |
158.00€
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Item number: Cay10009851-100
Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphatase cycle, as well as with Ins(1,4,5,6)P4 in a...
Keywords: | 1,3,4,5,6-IP5 (sodium salt), Ins(1,3,4,5,6)P5, D-myo-inositol-1,3,4,5,6-penta(hydrogen phosphate), decaammonium salt |
Application: | Bioactive lipid assays |
MW: | 750.4 D |
From 84.00€
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Item number: Cay10005098-10
AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide (AEA:...
Keywords: | 7-amino-4-methyl Coumarin-Arachidonamide, AMC-AA, 7-amino-4-methyl-2H-1-benzopyran-2-one-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 862913-13-1 |
MW: | 461.6 D |
From 109.00€
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Item number: Cay10006198-50
Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTC4 by GC- or LC-mass spectrometry. LTC4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione...
Keywords: | LTC4-d5, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid |
Application: | Standard |
CAS | 1441421-73-3 |
MW: | 630.8 D |
From 390.00€
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Item number: Cay10008198-50
Linoleic acid ethyl ester is an esterified form of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is active against the bacteria S. mutans, A. actinomycetemcomitans, P. gingivalis, S. gordonii, and S. sanguis and the fungus C. albicans when used at a concentration of 25 µg/ml. Linoleic acid ethyl ester (3...
Keywords: | C18:2 (cis-9,12) ethyl ester, Ethyl cis-9,12-Octadecadienoate, Ethyl Linoleate, Telfairic Acid ethyl ester,... |
Application: | Bioactive lipid assays |
CAS | 544-35-4 |
MW: | 308.5 D |
From 20.00€
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Item number: Cay10009598-1
6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 µM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6beta-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by...
Keywords: | 6,7-DHB, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octenyl]oxy]-7H-fuoro[3,2-g][1]benzopyran-7-one |
Application: | CYP3A4 inhibitor |
CAS | 145414-76-2 |
MW: | 372.4 D |
From 27.00€
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Item number: Cay10009518-1
MAP kinase kinase 1 (MAPKK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation . This pathway also plays a key role in synaptic plasticity in the brain . Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP...
Keywords: | MAP Kinase Kinase 1, MAPKK1, Mitogen-activated Protein Kinase Kinase 1 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
564.00€
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Item number: Cay10005-1
This mixture contains the primary metabolites of prostaglandins (PGs) D2, E2, and F2alpha. Contents: 13,14-dihydro-15-keto PGD2, 13,14-dihydro-15-keto PGE2, 11beta-PGF2alpha, 13,14-dihydro-15-keto PGF2alpha, and PGF2beta (100 µg each). In primates, the lung is an active site of PG inactivation via 15-hydroxy PG...
Keywords: | PG Metabolite HPLC Mixture |
Application: | Bioactive lipid assays |
130.00€
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Item number: Cay10005196-96
Cayman's FAAH Inhibitor Screening Assay Kit provides a convenient fluorescence-based method for screening FAAH inhibitors. FAAH hydrolyzes AMC arachidonoyl amide resulting in the release of the fluorescent product, 7-amino-4-methylcoumarin (AMC). The fluorophore can be easily analyzed using an excitation wavelength...
Keywords: | Anandamide Amidohydrolase, FAAH, Oleamide Hydrolase |
Application: | FAAH inhibitor screening |
Species reactivity: | human |
436.00€
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