16 products were found matching "Cay10005000"!

Stearidonic Acid (18:4omega-3) is a rare polyunsaturated fatty acid of the omega-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. It is present in certain natural oils such as echium and black currant seed, and to the extent that these oils are incorporated into...

Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base. Oligomers of PGB1 are known to exhibit antioxidant and ionophoric activity.Formal Name: 9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid. CAS Number: 13345-51-2. Synonyms: PGB1. Molecular Formula:...

Cellular prion protein (PrPc) is a cell surface glycoprotein expressed in brain, spinal cord, and several peripheral tissues that if mutated to the protease-resistant isoform PrPSc (scrapie PrP, PrPres) can result in one of several fatal neurodegenerative diseases. Prion diseases, including mad cow disease (bovine...

Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...

Concanamycin A is a plecomacrolide antibiotic that has been found in Streptomyces. It is active against S. cerevisiae, S. sake, A. citri, P. citrinum, and P. oryzae (MICs = +-ATPase (V-ATPase, EC50 = ~2.1-2.3 µM). It also decreases perforin levels in CD8+ OE4 cytotoxic T lymphocytes (CTLs). Concanamycin A (100 µM)...

4-biphenylthio Carboxamide is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: [1,1'-biphenyl]-4-carbothioamide. CAS Number: 13363-50-3. Synonyms: Biphenyl-4-Carbothioic Acid amide. Molecular Formula: C13H11NS. Formula Weight: 213.3. Purity: >98%. Formulation: (Request formulation change), A...

Colneleic acid is a divinyl ether oxylipin and an active metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) that has been found in potatoes. It is formed from linoleic acid by 9-lipoxygenase (9-LO) via a (±)9-HpODE (Cay-10705) intermediate and divinyl ether synthase. Colneleic acid decreases P....

Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-2 is a nutlin-3 analog in which trifluoromethyl groups have been substituted for chlorine on the 2 phenyl rings. At high concentrations, caylin-2 inhibits the growth of HCT116...

Eicosapentaenoic acid-d5 (EPA-d5) is intended for use as an internal standard for the quantification of EPA (Cay-90110, Cay-90110.1, Cay-26415) by GC- or LC-MS. EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively,...

Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Cay-90310) by GC- or LC-MS. DHA is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and...

L-NMMA is the archetypal competitive NOS inhibitor to which other inhibitors are often compared. It is a relatively non-selective inhibitor of all NOS isoforms. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively.Formal Name:...

CAY10455 is a labeled analog of arachidonoyl ethanolamide (anandamide, AEA) that is non-fluorescent when outside the cell. Upon transport into the cell interior, it is cleaved by esterases to give a bright fluorescence at 530 nm. CAY10455 uptake into C6 glioma cells is inhibited by AEA and its analogs, and...