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sPLA2 (Type V) Inhibitor Screening Assay Kit
sPLA2 (Type V) Inhibitor Screening Assay Kit

Item number: Cay10004883-96

Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid. The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell. Mammalian tissues contain...
Keywords: Secretory Phospholipase A2 (Type V)
Application: sPLA2 inhibitor screening
605.00€ *
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Erlotinib
Erlotinib

Item number: Cay10483-250

Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
Keywords: NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
Application: Tyrosine kinase inhibitor
CAS 183321-74-6
MW: 393.4 D
From 43.00€ *
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