3 products were found matching "Cay10004517-%25"!
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PPARdelta (human, recombinant)
Item number: Cay10007451-25
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. The PPAR family of nuclear hormone receptors consists of three subtypes...
| Keywords: | FAAR, NUC1, Nuclear Hormone Receptor 1, Peroxisome Proliferative Activated Receptor delta, PPARbeta |
| Application: | WB |
| MW: | 54 kD |
From 595.00€
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Matairesinol
Item number: Cay10005174-25
Matairesinol is a lignan that has been found in Forsythia and has diverse biological activities. It reduces LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2, Cay-14010) in RAW 264.7 cells. Matairesinol is cytotoxic to colon 26 cancer cells (LC50 = 9 µg/ml). It increases the lifespan of C....
| Keywords: | (-)-Matairesinol, dihydro-3R,4R-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |
| Application: | Metabolic studies |
| CAS | 580-72-3 |
| MW: | 358.4 D |
From 66.00€
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Tienilic Acid
Item number: Cay10008517-25
Cytochrome P450 enzymes function to metabolize both endogenous and exogenous compounds. Both the 3A and 2C isoforms are present in human liver of which CYP2C9 seems most highly expressed. Tienilic acid is a specific suicide substrate for CYP2C9 and CYP2C10 whereby its oxidation inactivates the enzyme. The time...
| Keywords: | [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]-acetic acid |
| Application: | CYP2C9 /CYP2C10 substrate |
| CAS | 40180-04-9 |
| MW: | 331.2 D |
From 97.00€
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