3 products were found matching "Cay10004385-%25"!

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16(R)-HETE
16(R)-HETE

Item number: Cay10004385-25

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the...
Keywords: 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 183509-22-0
MW: 320.5 D
From 196.00€ *
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16(S)-HETE
16(S)-HETE

Item number: Cay10004384-25

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase...
Keywords: 16S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 183509-23-1
MW: 320.5 D
From 196.00€ *
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Sulindac sulfide
Sulindac sulfide

Item number: Cay10004387-25

Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
Keywords: 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
Application: Aldose reductase inhibitor, COX1/COX2 inhibitor
CAS 49627-27-2
MW: 340.4 D
From 43.00€ *
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