3 products were found matching "Cay10004377-%25"!

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Sulindac sulfide
Sulindac sulfide

Item number: Cay10004387-25

Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
Keywords: 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
Application: Aldose reductase inhibitor, COX1/COX2 inhibitor
CAS 49627-27-2
MW: 340.4 D
From 43.00€ *
Review
alpha-Tocotrienol
alpha-Tocotrienol

Item number: Cay10008377-25

alpha-Tocotrienol is an antioxidant and a form of vitamin E that has been found in rice bran and has neuroprotective properties. It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 (Cay-82220), or L-buthionine-(S,R)-sulfoximine (BSO, Cay-14484) in rat striatal cultures when used at...
Keywords: 3,4-dihydro-2,5,7,8-tetramethyl-2R-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl)]-2H-1-benzopyran-6-ol
Application: Antioxidant, vitamin E form, neuroprotective agent
CAS 58864-81-6
MW: 424.7 D
From 43.00€ *
Review
CAY10443
CAY10443

Item number: Cay10004177-25

Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is...
Keywords: (S)-Indan-1-yl 3,4-dichlorobenzylcarbamate, [(3,4-dichlorophenyl)methyl]-carbamic acid, (1S)-2,3-dihydro-1H-inden-1-yl ester
Application: Caspase-3 activator
CAS 582314-48-5
MW: 336.2 D
From 66.00€ *
Review