4 products were found matching "Cay10004238-%25"!
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16(S)-HETE
Item number: Cay10004384-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase...
| Keywords: | 16S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 183509-23-1 |
| MW: | 320.5 D |
From 196.00€
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16(R)-HETE
Item number: Cay10004385-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the...
| Keywords: | 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 183509-22-0 |
| MW: | 320.5 D |
From 196.00€
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Sulindac sulfide
Item number: Cay10004387-25
Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
| Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid |
| Application: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
| CAS | 49627-27-2 |
| MW: | 340.4 D |
From 43.00€
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Sildenafil Citrate
Item number: Cay14008-25
Sildenafil is a potent inhibitor of phosphodiesterase 5 (PDE5) with IC50 values of 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively. It is selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 µM, respectively). Sildenafil reverses glucose-induced decreases...
| Keywords: | Apodefil, Tonafil, UK 92480,... |
| Application: | Phosphodiesterase type 5 inhibitor |
| CAS | 171599-83-0 |
| MW: | 666.7 D |
From 65.00€
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