- Search results for Cay10004238
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8 products were found matching "Cay10004238"!
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Item number: Cay10004384-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase...
Keywords: | 16S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 183509-23-1 |
MW: | 320.5 D |
From 196.00€
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Item number: Cay10004385-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the...
Keywords: | 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 183509-22-0 |
MW: | 320.5 D |
From 196.00€
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Item number: Cay10004387-25
Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid |
Application: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
CAS | 49627-27-2 |
MW: | 340.4 D |
From 43.00€
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Item number: Cay10004235-10
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol...
Keywords: | (Z)-Resveratrol, 5[(1Z)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol |
Application: | NAD(P)H oxidase inhibitor |
CAS | 61434-67-1 |
MW: | 228.2 D |
From 100.00€
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Item number: Cay10004236-10
2-arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases to...
Keywords: | Flu-SA,... |
Application: | CB1 receptor agonist |
CAS | 1176658-85-7 |
MW: | 531.6 D |
From 82.00€
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Item number: Cay10004237-10
2-Arachidonyl glycerol (2-AG) exhibits cannabinoid agonist activity at the central cannabinoid (CB1) receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by COX-2 to form prostaglandin (PG) 2-glyceryl esters....
Keywords: | 17-phenyl trinor PGF2alpha-SA, Bimatoprost serinol amide,... |
Application: | Bioactive lipid assays |
CAS | 1175838-84-2 |
MW: | 461.6 D |
From 98.00€
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Item number: Cay23804-100
Benazepril is a prodrug of the angiotensin converting enzyme (ACE) inhibitor benazeprilat (Cay-21796). It is metabolized to benazeprilat by hepatic esterases. Benazepril inhibits the in vitro enzymatic activity of partially purified ACE isolated from rabbit lung (IC50 = 2 nM). It decreases the triglyceride and total...
Keywords: | CGS 14824A, (3S)-3-[[1S-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid,... |
Application: | ACE inhibitor prodrug |
CAS | 86541-74-4 |
MW: | 461 D |
From 77.00€
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Item number: Cay10038-10
CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids, eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making...
Keywords: | 2,3',4,5'-Tetramethoxystilbene, 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene |
Application: | CYP1B1 inhibitor |
CAS | 24144-92-1 |
MW: | 300.4 D |
From 22.00€
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