- Search results for Cay100029
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5 products were found matching "Cay100029"!
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Item number: Cay100029-1
beta-Catenin is a transcriptional coactivator that is encoded by the CTNNB1 gene in humans. It is a 781 amino acid protein comprised of an N-terminal domain containing glycogen synthase kinase 3beta (GSK3beta) phosphorylation sites, a C-terminal transactivation domain, and a central domain spanning amino acid...
Keywords: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Beta-catenin, Anti-Catenin beta-1, Anti-Catenin beta-1 |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay10029-5
MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...
Keywords: | L-660,711, (E)-3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic... |
Application: | CysLT1 receptor antagonist |
CAS | 115104-28-4 |
MW: | 515.1 D |
From 43.00€
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Item number: Cay11029-5
The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of rapamycin (mTORC1), which regulates cell growth and survival. Pim kinases are overexpressed in solid cancers and hematologic malignancies, and as such have become targets of small molecule...
Keywords: | 5Z-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione |
Application: | Pim-1/Pim-2 kinase inhibitor |
CAS | 438190-29-5 |
MW: | 273.2 D |
From 60.00€
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Item number: Cay10229-1
Amyloid-beta (1-8, A2V) is a truncated form of amyloid-beta (Abeta) that contains a valine to alanine substitution at position 2 of the Abeta numbering convention (Abeta A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Abeta (1-40) (Abeta40) A2V...
Keywords: | Amyloid-beta (1-8) dominant negative, Abeta (1-8) mutant, Abeta (1-8, A2V) |
Application: | Biochemical assays |
MW: | 1004 D |
102.00€
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Item number: Cay10009929-100
SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.Formal Name:...
Keywords: | Suberoylanilide Hydroxamic Acid, Vorinostat, N1-hydroxy-N8-phenyl-octanediamide |
Application: | HDAC inhibitor |
CAS | 149647-78-9 |
MW: | 264.3 D |
From 34.00€
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