17 products were found matching "Cay100027-%25"!

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DL-alpha-Lipoic Acid
DL-alpha-Lipoic Acid

Item number: Cay10005728-25

DL-alpha-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle, and acts as a general antioxidant. DL-alpha-lipoic acid can act as a direct radical scavenger, as a cofactor to regenerate...
Keywords: Thioctic Acid, 1,2-dithiolane-3-pentanoic acid
Application: Antioxidant
CAS 1077-28-7
MW: 206.3 D
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1,2,3-Trieicosapentaenoyl Glycerol
1,2,3-Trieicosapentaenoyl Glycerol

Item number: Cay10009732-25

1,2,3-Trieicosapentaenoyl glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid (Cay-90110, Cay-21908), which is an omega-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonuclear leukocytes from rabbits and reduces platelet aggregation. It suppresses...
Keywords: EPA-TG, Glycerol Trieicosapentaenoate, TG(20:5/20:5/20:5),...
CAS 99660-94-3
MW: 945.4 D
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Palmitic Acid
Palmitic Acid

Item number: Cay10006627-25

Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid...
Keywords: C16:0, hexadecanoic acid
Application: Bioactive lipid assays
CAS 57-10-3
MW: 256.4 D
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(±)14(15)-EpEDE
(±)14(15)-EpEDE

Item number: Cay10007527-25

8,11,14-Eicosatrienoic acid, also known as dihomo-gamma-linolenic acid (Cay-90230), is a polyunsaturated fatty acid (PUFA) produced from gamma-linolenic acid by the action of fatty acid elongases. It can be metabolized by the cyclooxygenase pathway to produce 1-series prostaglandins (PGs) (e.g., PGE1)....
Keywords: (±)14,15-Epoxyeicosadienoic Acid, (±)13-(3-pentyl-2-oxiranyl)-8Z,11Z-tridecadienoic acid
Application: Lipid studies
CAS 351533-80-7
MW: 322.5 D
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5-Chlororesorcinol dimethyl ether
5-Chlororesorcinol dimethyl ether

Item number: Cay10007127-25

5-Chloroesorcinol dimethyl ether is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 1-chloro-3,5-dimethoxy-benzene. CAS Number: 7051-16-3. Synonyms: NSC 220095. Molecular Formula: C8H9ClO2. Formula Weight: 172.6. Purity: >98%. Formulation: (Request formulation change), A liquid. Solubility:...
Keywords: NSC 220095, 1-chloro-3,5-dimethoxy-benzene
Application: Synthetic intermediate, pharmaceutical synthesis
CAS 7051-16-3
MW: 172.6 D
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PD 169316
PD 169316

Item number: Cay10006727-25

p38 is a member of the mitogen-activated protein kinase (MAPK) superfamily of enzymes that play an important role in signal transduction. PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK)...
Keywords: 4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl]-pyridine
Application: p38 MAPK inhibitor
CAS 152121-53-4
MW: 360.3 D
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19(S)-HETE
19(S)-HETE

Item number: Cay10007766-25

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators...
Keywords: 19S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 115461-40-0
MW: 320.5 D
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(±)-EX-527
(±)-EX-527

Item number: Cay10009798-25

EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7...
Keywords: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Application: SIRT1 inhibitor
CAS 49843-98-3
MW: 248.7 D
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19(R)-HETE
19(R)-HETE

Item number: Cay10007767-25

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators...
Keywords: 19R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 115461-39-7
MW: 320.5 D
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CAY10591
CAY10591

Item number: Cay10009797-25

Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Keywords: SIRT1 Activator 3, Sirtuin 1 Activator 3,...
Application: SIRT1 assays
CAS 839699-72-8
MW: 367.5 D
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AS-605240
AS-605240

Item number: Cay10007707-25

Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the three position to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kgamma is a class 1B PI3K that is composed of a p110 catalytic subunit and a p101 or p84 regulatory subunit, whereas PI3Kalpha,...
Keywords: 5-(6-quinoxalinylmethylene)-2,4-thiazolidinedione
Application: PI3K inhibitor
CAS 648450-29-7
MW: 257.3 D
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GW 0742
GW 0742

Item number: Cay10006798-25

The transcription factor peroxisome proliferator-activated receptor delta (PPARdelta) is a member of the superfamily of nuclear hormone receptors and is implicated both in lipid metabolism and in the regulation of genes with potential roles in neurotoxicity. GW 0742 is a selective PPARdelta agonist (EC50 = 1.1 nM)...
Keywords: GW 610742, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-acetic acid
Application: PPARdelta agonist
CAS 317318-84-6
MW: 471.5 D
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