- Search results for Cay100022-%25
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6 products were found matching "Cay100022-%25"!
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Item number: Cay10009222-25
Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
Keywords: | SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol |
Application: | SPHK1 inhibitor |
CAS | 312636-16-1 |
MW: | 302.8 D |
From 54.00€
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Item number: Cay10008822-25
Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...
Keywords: | LDP-341, MG-341, MLN341, NSC 681239, PS-341,... |
Application: | Proteasome subunit beta type-1/5 inhibitor |
CAS | 179324-69-7 |
MW: | 384.2 D |
From 43.00€
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Item number: Cay10007280-25
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D5 (RvD5) is a DHA-derived...
Keywords: | 7(S),17(S)-diHDHA, 7(S),17(S)-Resolvin D5, RvD5, 7S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acid |
Application: | Lipid mediator |
CAS | 578008-43-2 |
MW: | 360.5 D |
From 205.00€
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Item number: Cay10009280-25
L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of...
Keywords: | 3-(1,1-dimethylheptyl)-6aR,7,10,10aR-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
Application: | CB2 receptor agonist |
CAS | 174627-50-0 |
MW: | 384.6 D |
From 42.00€
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Item number: Cay10007295-25
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Anandamide (AEA) is an endogenous...
Keywords: | Arachidonamide, Arachidonic Acid amide, 5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 85146-53-8 |
MW: | 303.5 D |
From 56.00€
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Item number: Cay10009210-25
Phosphatidylinositol 3-kinase (PI3K) catalyzes the synthesis of the second messengers PtdIns-(3)-P, PtdIns-(3,4)-P2, and PtdIns-(3,4,5)-P3. The PI3K family of enzymes is comprised of 15 members that are divided into three classes according to their structure, substrate specificity, and mode of regulation. In the...
Keywords: | 2-methyl-5-nitro-2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide-benzenesulfonic acid, monohydrochloride |
Application: | p110a inhibitor |
CAS | 372196-77-5 |
MW: | 488.7 D |
From 34.00€
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