- Search results for Cay10002
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14 products were found matching "Cay10002"!
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Item number: Cay10002-1
This mixture contains primary prostaglandins produced from arachidonic acid and dihomo-gamma-linolenic acid. Contents: Prostaglandin E1, Prostaglandin E2, Prostaglandin F1alpha, 6-keto Prostaglandin F1alpha, and Prostaglandin F2alpha (100 µg each).Synonyms: PG HPLC Mixture. Purity: >98% for each compound....
Keywords: | PG HPLC Mixture |
Application: | Bioactive lipid assays |
113.00€
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Item number: Cay11102-500
The lysine methyltransferase EZH2 (KMT6), part of the polycomb repressive complex 2, catalyzes trimethylation of lysine 27 on histone H3 and is involved in proliferation and aggressive cell growth associated with neoplastic cells. 3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally...
Keywords: | 2,3-DMMC, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride |
CAS | 120964-45-6 |
MW: | 298.7 D |
From 123.00€
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Item number: Cay11022-10
BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
Keywords: | Nintedanib,... |
Application: | Receptor tyrosine kinase inhibitor |
CAS | 656247-17-5 |
MW: | 539.6 D |
From 60.00€
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Item number: Cay10022-50
F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
Keywords: | 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide |
Application: | Antitumor agent, Apoptosis inducer |
CAS | 36098-33-6 |
MW: | 362.2 D |
From 19.00€
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Item number: Cay100022-1
Hepsin is a type II membrane-associated protein that has an extracellular proteolytic domain and exhibits low sequence homology to other known proteases. Hepsin overexpression is observed in prostate, breast, kidney, and ovarian cancers and due to low homology to other known proteases may provide a unique target for...
Keywords: | Anti-HPN, Anti-TMPRSS1, Anti-Serine protease hepsin, Anti-Transmembrane protease serine 1, Anti-Serine protease hepsin... |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay100002-1
Optineurin (originally named FIP-2) is a 74 kDa protein implicated in signal transduction of the tumor necrosis factor (TNF) pathway as well as membrane traffic regulation and cellular morphogenesis. Optineurin protein is also involved in apoptosis, although the exact role is currently unknown. Increased apoptosis...
Keywords: | Anti-OPTN, Anti-FIP2, Anti-FIP-2, Anti-HIP-7, Anti-FIP-2, Anti-HIP-7, Anti-Optineurin, Anti-Optineurin, Anti-TFIIIA-IntP,... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay10222-100
Protein phosphorylation is an important post-translational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently...
Application: | ELISA, WB |
Host: | Mouse |
530.00€
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Item number: Cay100027-1
Sterol O-acyltransferase 2 (SOAT-2), also known as acyl-coenzyme A:cholesterol acyltransferase-2 (ACAT-2), is an enzyme encoded by ACAT2 in humans that catalyzes the intracellular formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A. It is constitutively expressed in the liver and...
Keywords: | Anti-ACACT2, Anti-ACAT-2, Anti-ACAT-2, Anti-Cholesterol acyltransferase 2, Anti-Cholesterol acyltransferase 2, Anti-Sterol... |
Application: | IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay100028-1
Sterol O-acyltransferase 1 (SOAT-1), also known as acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1), is an enzyme encoded by ACAT1 in humans that catalyzes the intracellular formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A. It is ubiquitously expressed and localized to the...
Keywords: | Anti-ACAT-1, Anti-ACAT-1, Anti-Sterol O-acyltransferase 1, Anti-Sterol O-acyltransferase 1, Anti-Cholesterol... |
Application: | IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay100023-1
PGIS catalyzes the isomerization of PGH2 to PGI2. PGI2 (prostacyclin) is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells. The cloned bovine and human enzymes contain 500 amino acids and a calculated molecular mass of 56,629 and...
Keywords: | Anti-Cyp8, Anti-Ptgis, Anti-Prostacyclin synthase, Anti-Prostacyclin synthase, Anti-Prostaglandin I2 synthase,... |
Application: | IHC, WB |
Host: | Rabbit |
422.00€
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Item number: Cay100020-500
Immunogen: purified eggshell proteins (Zrp and small amounts of zona pellucida proteins) from Atlantic salmon (S. salar). Clone Designation: MN-2B4. Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 mM sodium azide....
Application: | WB, ELISA |
Host: | Mouse |
Species reactivity: | atlantic salmon |
From 385.00€
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Item number: Cay100025-1
5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OxoETE) is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediates its action via a putative G-protein coupled receptor (GPCR). The 5-OxoETE receptor couples to Gi/o to inhibit cyclic AMP production and to mobilize intracellular calcium. Northern...
Keywords: | Anti-OXER1, Anti-GPR170, Anti-Oxoeicosanoid receptor 1, Anti-Oxoeicosanoid receptor 1, Anti-G-protein coupled receptor... |
Application: | ICC, WB |
Host: | Rabbit |
Species reactivity: | human, murine, rat, swine, Cos-7 |
422.00€
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