14 products were found matching "Cay10002"!

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Prostaglandin HPLC Mixture
Prostaglandin HPLC Mixture

Item number: Cay10002-1

This mixture contains primary prostaglandins produced from arachidonic acid and dihomo-gamma-linolenic acid. Contents: Prostaglandin E1, Prostaglandin E2, Prostaglandin F1alpha, 6-keto Prostaglandin F1alpha, and Prostaglandin F2alpha (100 µg each).Synonyms: PG HPLC Mixture. Purity: >98% for each compound....
Keywords: PG HPLC Mixture
Application: Bioactive lipid assays
113.00€ *
Review
3-Deazaneplanocin A (hydrochloride)
3-Deazaneplanocin A (hydrochloride)

Item number: Cay11102-500

The lysine methyltransferase EZH2 (KMT6), part of the polycomb repressive complex 2, catalyzes trimethylation of lysine 27 on histone H3 and is involved in proliferation and aggressive cell growth associated with neoplastic cells. 3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally...
Keywords: 2,3-DMMC, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride
CAS 120964-45-6
MW: 298.7 D
From 123.00€ *
Review
BIBF 1120
BIBF 1120

Item number: Cay11022-10

BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
Keywords: Nintedanib,...
Application: Receptor tyrosine kinase inhibitor
CAS 656247-17-5
MW: 539.6 D
From 60.00€ *
Review
F16
F16

Item number: Cay10022-50

F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
Keywords: 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide
Application: Antitumor agent, Apoptosis inducer
CAS 36098-33-6
MW: 362.2 D
From 19.00€ *
Review
Anti-Hepsin   (aa 241-260)
Anti-Hepsin (aa 241-260)

Item number: Cay100022-1

Hepsin is a type II membrane-associated protein that has an extracellular proteolytic domain and exhibits low sequence homology to other known proteases. Hepsin overexpression is observed in prostate, breast, kidney, and ovarian cancers and due to low homology to other known proteases may provide a unique target for...
Keywords: Anti-HPN, Anti-TMPRSS1, Anti-Serine protease hepsin, Anti-Transmembrane protease serine 1, Anti-Serine protease hepsin...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human
422.00€ *
Review
Anti-Optineurin (INT)
Anti-Optineurin (INT)

Item number: Cay100002-1

Optineurin (originally named FIP-2) is a 74 kDa protein implicated in signal transduction of the tumor necrosis factor (TNF) pathway as well as membrane traffic regulation and cellular morphogenesis. Optineurin protein is also involved in apoptosis, although the exact role is currently unknown. Increased apoptosis...
Keywords: Anti-OPTN, Anti-FIP2, Anti-FIP-2, Anti-HIP-7, Anti-FIP-2, Anti-HIP-7, Anti-Optineurin, Anti-Optineurin, Anti-TFIIIA-IntP,...
Application: IHC, WB
Host: Rabbit
Species reactivity: human
422.00€ *
Review
Anti-Phosphotyrosine (Ascites)   (Clone 13F9)
Anti-Phosphotyrosine (Ascites) (Clone 13F9)

Item number: Cay10222-100

Protein phosphorylation is an important post-translational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently...
Application: ELISA, WB
Host: Mouse
530.00€ *
Review
Anti-SOAT-2/ACAT-2
Anti-SOAT-2/ACAT-2

Item number: Cay100027-1

Sterol O-acyltransferase 2 (SOAT-2), also known as acyl-coenzyme A:cholesterol acyltransferase-2 (ACAT-2), is an enzyme encoded by ACAT2 in humans that catalyzes the intracellular formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A. It is constitutively expressed in the liver and...
Keywords: Anti-ACACT2, Anti-ACAT-2, Anti-ACAT-2, Anti-Cholesterol acyltransferase 2, Anti-Cholesterol acyltransferase 2, Anti-Sterol...
Application: IF, IHC, WB
Host: Rabbit
Species reactivity: human
422.00€ *
Review
Anti-SOAT-1/ACAT-1
Anti-SOAT-1/ACAT-1

Item number: Cay100028-1

Sterol O-acyltransferase 1 (SOAT-1), also known as acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1), is an enzyme encoded by ACAT1 in humans that catalyzes the intracellular formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A. It is ubiquitously expressed and localized to the...
Keywords: Anti-ACAT-1, Anti-ACAT-1, Anti-Sterol O-acyltransferase 1, Anti-Sterol O-acyltransferase 1, Anti-Cholesterol...
Application: IF, IHC, WB
Host: Rabbit
Species reactivity: human
422.00€ *
Review
Anti-Prostaglandin I Synthase (mouse)
Anti-Prostaglandin I Synthase (mouse)

Item number: Cay100023-1

PGIS catalyzes the isomerization of PGH2 to PGI2. PGI2 (prostacyclin) is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells. The cloned bovine and human enzymes contain 500 amino acids and a calculated molecular mass of 56,629 and...
Keywords: Anti-Cyp8, Anti-Ptgis, Anti-Prostacyclin synthase, Anti-Prostacyclin synthase, Anti-Prostaglandin I2 synthase,...
Application: IHC, WB
Host: Rabbit
422.00€ *
Review
Anti-Zona Radiata (salmon)   (Clone MN-2B4)
Anti-Zona Radiata (salmon) (Clone MN-2B4)

Item number: Cay100020-500

Immunogen: purified eggshell proteins (Zrp and small amounts of zona pellucida proteins) from Atlantic salmon (S. salar). Clone Designation: MN-2B4. Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 mM sodium azide....
Application: WB, ELISA
Host: Mouse
Species reactivity: atlantic salmon
From 385.00€ *
Review
Anti-5-OxoETE Receptor
Anti-5-OxoETE Receptor

Item number: Cay100025-1

5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OxoETE) is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediates its action via a putative G-protein coupled receptor (GPCR). The 5-OxoETE receptor couples to Gi/o to inhibit cyclic AMP production and to mobilize intracellular calcium. Northern...
Keywords: Anti-OXER1, Anti-GPR170, Anti-Oxoeicosanoid receptor 1, Anti-Oxoeicosanoid receptor 1, Anti-G-protein coupled receptor...
Application: ICC, WB
Host: Rabbit
Species reactivity: human, murine, rat, swine, Cos-7
422.00€ *
Review
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