LSD-1 Fluorescent assay kit
ART NR.: BPS-50107 (400 rxns)
Anwendungen: Enzyme kinetics, inhibitor screening, HTS
UniProt ID: O60341
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Schlagworte: LSD1 demethylase assay kit AOF2, KDM1A, EC=1.-.-.-, BRAF35-HDAC complex protein BHC110, Lysine-specific histone demethylase 1A, Flavin-containing amine oxidase domain-containing protein 2
The LSD1 Assay Kit is designed to detect LSD1 activity using fluorimetry. The assay is based on the analysis of the hydrogene peroxide produced during the demethylation reaction mediated by LSD1. Human lysine-specific demethylase, LSD1, is a chromatin-modifying enzyme that specifically removes methyl groups from mono- and dimethylated Lys of histone H3. LSD1 is a potential target for drug development. The LSD1 Assay Kit comes in a convenient 384-well format, with purified LSD1, Amplex Red reagent, peroxidase, and LSD1 assay buffer for 384 enzyme reactions. The key to the LSD1 Assay Kit is the methylated peptide substrate. Using this kit, only two simple steps on a microtiter plate are required for LSD1 reactions.
Products for: AOF2, LSD1 - lysine-specific histone demethylase 1 [EC:1.-.-.-]