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BPS-33000 BET Bromodomain Ligand BPS
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500 µl

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440 €

BET Bromodomain Ligand


Binding assays, inhibitor screening, selectivity profiling Erklärungen der Abkürzungen ansehen.

The BET Bromodomain Ligand is peptide histone H4 (1-21), acetylated at lysine 5, 8, 12 and 16. It contains a C-terminal GG linker, followed by a biotinylated Lys. Bromodomains function as acetyl-lysine binding domains, and bromodomain/acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. This peptide is suitable for use as a ligand for several bromodomains including members of the BET bromodomain family: BRD2, BRD3, BRD4, and BRDT. Supplied as a 2 µM solution.

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