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RG-7090
RG-7090

Item number: Cay36806-1

RG-7090 is a negative allosteric modulator of metabotropic glutamate receptor 5 (mGluR5). It binds to mGluR5 (Ki = 35.6 nM) and is selective for mGluR5 over a panel of 116 additional receptors at 10 µM. RG-7090 inhibits quisqualate-induced calcium mobilization and inositol phosphate accumulation in HEK293 cells...
Keywords: Basimglurant, RO4917523, 2-chloro-4-[2-[1-(4-fluorophenyl)-2,5-dimethyl-1H -imidazol-4-yl]ethynyl]-pyridine
Application: MGluR5 negative allosteric modulator
CAS 802906-73-6
MW: 325.8 D
From 114.00€ *
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